These nevi is an unique variety of keratinocytic epidermal nevus, which exhibit both psoriasiform
and inflammatory features.
1) Although Basex syndrome remains a rare paraneoplastic manifestation, psoriasiform
lesions occurring in a smoking and drinking patient must lead to the suspicion of an aerodigestive tract neoplasia and could require an ENT consultation.
eruption associated with graft-versus-host disease.
At moderate concentrations of imiquimod, there was enhanced psoria-form dermatitis in mice that had PD-1 blockade, suggesting that PD-1 might have a regulatory function in psoriasiform
A 4-year old Iranian girl was referred to the Mazandaran University Hospital, Sari complaining of well-demarcated, psoriasiform
, yellowish, keratotic plaques over the skin of her palms and soles with transgrediens.
A skin biopsy demonstrated psoriasiform
dermatitis with alternating areas of orthokeratosis and parakeratosis (the presence of keratinocyte nuclei within the stratum corneum where nuclei typically aren't found).
Paradoxical effects of anti TNF-alpha drugs represent a new onset or exacerbation of a condition that is normally improved through the use of the same biological therapy; psoriasis, psoriasiform
eruption, and eczema are the most frequently observed.
Vleugels emphasized that it's important not to miss a more subtle, less violaceous heliotrope eruption, especially in lighter-skinned patients; similarly, Gottron's papules are not always papular and limited to the knuckle pads, but can be more macular and linear, with psoriasiform
The presence or absence of eosinophils can also be helpful in distinguishing a psoriasiform
spongiotic reaction (often present) from psoriasis (absent), or a lichenoid drug reaction (present) (Figure 3, A and B) from lupus erythematosus (absent).
1) Clinically, it can present with psoriasiform
skin lesions in acral distribution with variable whitish scaling.
Prolactin induces the production of Th 17 and Th1 cytokines/chemokines in murine Imiquimod-induced psoriasiform
The histopathological findings are parakeratosis and psoriasiform
hyperplasia with neutrophilic infiltration into the epithelium.