psoralen


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Related to psoralen: Methoxsalen

psoralen

 [sor´ah-len]
any of the constituents of certain plants, such as Psoralea corylifolia, that have the ability to produce phototoxic dermatitis when an individual is first exposed to it and then to sunlight; certain perfumes and drugs, such as methoxsalen, contain psoralens.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

psor·a·len

(sōr'ă-len),
A phototoxic drug used by topical or oral administration for the treatment of vitiligo and psoriasis. Also present in oil of bergamot perfume and in fruits and vegetables such as limes, which may cause photosensitization.
See also: PUVA.
Farlex Partner Medical Dictionary © Farlex 2012

psoralen

(sôr′ə-lən)
n.
Any of a group of chemical compounds found in certain plants, used to treat psoriasis and vitiligo.
The American Heritage® Medical Dictionary Copyright © 2007, 2004 by Houghton Mifflin Company. Published by Houghton Mifflin Company. All rights reserved.

psoralen

Therapeutics A class of furocoumarins used to treat psoriasis and other skin conditions
McGraw-Hill Concise Dictionary of Modern Medicine. © 2002 by The McGraw-Hill Companies, Inc.

psor·a·len

(sōr'ă-len)
A phototoxic drug used topically or orally to treat vitiligo and psoriasis; present in oil of bergamot perfume and in fruits and vegetables such as limes, which may cause photosensitization.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

Psoralen

A family of photosensitizing chemicals that can be found in lemons, celery, and other plants. Chemically synthesized versions are used to augment the effects of UVA light treatments.
Mentioned in: Ultraviolet Light Treatment
Gale Encyclopedia of Medicine. Copyright 2008 The Gale Group, Inc. All rights reserved.
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References in periodicals archive ?
In another study by Parsad et al24, they compared PUVASOL (oral psoralen combined with ultraviolet A from sunlight) used alone with a combination of calcipotriol and PUVASOL in right vs left comparative trial.
COMPARISON OF EFFICACY OF TOPICAL CALCIPOTRIENE PLUS BETAMETHASONE WITH CALCIPOTRIENE ALONE IN LOCALIZED VITILIGO
Eomatium foeniculaceum, Iva axillaris, Psoralen argophylla are expected to do well on heavy soils, while Astragalus missouriensis and Allium textile are more appropriate for fields on lighter soils.
Choosing Native Species for Restoring Crested Wheatgrass Fields on the Great Plains of Northeast Montana
For more extensive involvement antihistamines, oral retinoids (isotretinoin, acitretin), methotrexate, allopurinol, or phototherapy [7, 8] (narrowband UV-B, broad band UV-B, or psoralen UV-A) may be appropriate.
Acquired Perforating Dermatosis in a Patient on Peritoneal Dialysis: A Case Report and Review of the Literature
Treatment modalities such as topical corticosteroids, topical calcineurin inhibitors, topical retinoids, narrowband ultraviolet B phototherapy, psoralen and ultraviolet irradiation, and oral acitretin have been used with varying success [2,15,16].
An 8-Year-Old Child with Delayed Diagnosis of Netherton Syndrome
As an alternative to these approaches, psoralen derivatives and long-wave ultraviolet light treatment can photo-react and irreversibly cross-link viral nucleic acids inside antigen-presenting cells, eliminating viral infectivity [10] while leaving surface molecules relatively unmodified.
Photochemical Treatment of Drosophila APCs Can Eliminate Associated Viruses and Maintain the APC Function for Generating Antigen-Specific CTLs Ex Vivo
Phototoxic effects of the drugs can also be used for therapeutic purposes, e.g., application of a photosensitizer such as psoralen and aminolevulinic acid.
DRUG-INDUCED PHOTOSENSITIVITY--A CONTINUING DIAGNOSTIC CHALLENGE
Treatments for more advanced psoriasis include narrow-band ultraviolet B (UVB) light, psoralen with ultraviolet A (UVA) light retinoids (isotretinoin [Accutane, Claravis], acitretin [Soriatane]), methotrexate (particularly for arthritis), cyclosporine (Neoral, Sandimmune), infliximab (Remicade), etanercept (Enbrel), adalimumab (Humira), apremilast (Otezla), and secukinumab (Cosentyx).
Psoriasis Treatment Market by Drug Classes, Therapies, Distribution Channel and Forecast to 2021, Upcoming Report by iHealthcareAnalyst, Inc.
However, psoralen with ultraviolet A (PUVA) treatment is not recommended because the psoralen can enter breastmilk and lead to light sensitivity (AAD, 2016).
A guide to common skin disorders while pregnant
As the main active component of Psoralea corylifolia L., psoralen was reported possessing cartilage protecting [7], antitumor [8, 9], immunomodulatory [10], antivitiligo [11], and antiurticaria activities [12].
Psoralen Inhibited Apoptosis of Osteoporotic Osteoblasts by Modulating IRE1-ASK1-JNK Pathway
She used topical tacrolimus, pimecrolimus, mometasone furoate cream, clobetasol propionate cream, topical psoralen combined with photochemotherapy with UVA, intramuscular triamcinolone acetonide, intramuscular alefacept, subcutaneous etanercept, oral cyclosporine, oral dapsone, and oral prednisone in the past.
Repigmentation of Tenacious Vitiligo on Apremilast
Psoralen, an effective component isolated from Fructus Psoraleae, dose-dependently enhances the production of GAG and type II collagen and increases the expression of SOX9 [100].
Insights into the Action Mechanisms of Traditional Chinese Medicine in Osteoarthritis

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