psilocybin


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psilocybin

 [si″lo-si´bin]
a hallucinogen having indole characteristics, isolated from the mushroom Psilocybe mexicana.

psi·lo·cy·bin

(sī'lō-sī'bin),
The N',N' -dimethyl derivative of 4-hydroxytryptamine; obtained from the fruiting bodies of the fungus Psilocybe mexicana and other species of Psilocybe and Stropharia. Psilocybin is a congener of 5-hydroxytryptamine, with striking central nervous system effects, and is readily hydrolyzed to 4-hydroxybufotenine; used as a hallucinogenic agent (and by native Mexicans to induce trances).
Synonym(s): indocybin

psilocybin

(sĭl′ə-sī′bĭn, sī′lə-)
n.
A hallucinogenic compound, C12H17N2O4P, obtained from mushrooms chiefly of the genus Psilocybe.

psi·lo·cy·bin

(sī'lō-sī'bin)
Fungal agent used as a hallucinogen (and by native Mexicans to induce trances).
Synonym(s): indocybin.

psilocybin

A powerfully hallucinogenic phosphorylated tryptamine present in the fungi contaminating some types of mushrooms, especially in Psilocybe mexicana . It is a powerful hallucinogenic drug with properties similar to those of LSD.
References in periodicals archive ?
Concerning psilocybin for alcohol use disorder (AUD), Dr.
Though possession of psilocybin mushrooms is illegal in the U.S., there are other countries where consumption of the mushroom variety is legal.
A recent preliminary, openlabel study has shown significant improvement in depressive symptoms following psilocybin administration with psychological support.
Any still on antidepressants will have these tapered off prior to the administration of a single dose of psilocybin. They will be supported by two trained facilitators for six hours on the dosing day, in a quiet safe clinical environment.
When Leary started the Harvard Psilocybin Project in 1960, Pollan notes, "there had already been a full decade of psychedelic research in North America, with hundreds of academic papers and several international conferences to show for it." Pollan does a real service by setting the record straight on this point in detail, showing that psychedelics' potential for facilitating psychotherapy, promoting the rehabilitation of addicts, and relieving end-of-life anxiety--applications that researchers are once again starting to investigate with the government's permission--were getting serious attention long before Leary arrived on the scene.
The company is developing psilocybin therapy through a late-stage clinical trial in Europe and North America for patients with treatment-resistant depression.
Psilocybin mushrooms are consumed in many ways, fresh or dried and, for example, some people brew them into tea or put them into food.
Psilocybin must clear phase III clinical trials before the FDA can be petitioned to reclassify it, which could happen in the next five years.
The naturally occurring psychoactive compound psilocybin in psilocybin mushrooms or 'magic mushrooms' gave the brain a 'kick start' to break out of depressive states.
Dr Robin Carhart-Harris, head of psychedelic research at Imperial College London, said: "We have shown for the first time clear changes in brain activity in depressed people treated with psilocybin after failing to respond to conventional treatments.
Imperial College London researchers used psilocybin - the psychoactive compound that occurs naturally in magic mushrooms - to treat a small number of patients with depression, monitoring their brain function, before and after.
Researchers from Imperial College London in the UK used psilocybin - the psychoactive compound that occurs naturally in magic mushrooms - to treat a small number of patients with depression in whom conventional treatment had failed.