We report a unique case of pseudotumour cerebri
and herpes encephalitis resulting due to isotretinoin.
CSF opening pressure (OP) readings are a vital component of LPs and results often play an important role in guiding both diagnosis and management of patients with conditions such as cryptococcal meningitis, tuberculous meningitis, pseudotumour cerebri
and normal-pressure hydrocephalus.
in children: etiological, clinical features and treatment modalities.
It showed prominent subarachnoid space around the optic nerves and a partial empty sella turcica, compatible with diagnosis of pseudotumour cerebri
From pseudotumour cerebri
to idiopathic intracranial hypertension.
as a side effect of leuprorelin acetate.
Causes include congenital arteriovenous aneurysm, cerebral tumor, spinal cord tumor, pseudotumour cerebri
, congenital hydrocephalus with trauma, subdural hematoma, subarachnoid hemorrhage, vascular hypertension, albuminuric retinitis, inflammatory meningeal and cerebral involvement with orbital involvement with ocular involvement with sinusitis and in blood dyscrasias.
a Pseudotumour cerebri
b Metastatic intracranial tumour c Aqueductal stenosis d Multiple sclerosis B A woman aged 28 presents with a four-day history of severe throbbing headache and transient episodes of visual loss (lasting seconds).
The medial aspect of the temporal bone may fail to develop, resulting in a persistent lateral craniopharyngeal canal (also known as the Sternberg canal) between the middle cranial fossa and the pneumatised inferolateral recess of the sphenoid sinus.3 Idiopathic intracranial hypertension (pseudotumour cerebri
) and empty sella syndrome are also known to occur in these patients,2 suggesting that chronically increased intracranial pressure with localised thinning of the bone may also play a role in the pathogenesis of this condition.4
Other significant adverse events (psychiatric disorders, pseudotumour cerebri
, decreased night vision, corneal opacities, inflammatory bowel disease, hyperostosis, hepatotoxicity and hypertriglyceridemia) have also been reported.26
Altered cerebrospinal fluid dynamics might occur with Chiari syndrome and pseudotumour cerebri
, causing diplopia.