pseudorosette

pseu·do·ro·sette

(sū'dō-rō-zet'),
Perivascular radial arrangement of neoplastic cells around a small blood vessel. See: rosette (2).

pseu·do·ro·sette

(sū'dō-rō-zet')
Perivascular radial arrangement of neoplastic cellsaround a small blood vessel.
See also: rosette (2)
References in periodicals archive ?
Frequent mitoses and few tumor giant cells were regarded along with subendothelial infiltrate and occasional pseudorosette (Figures 6 and 7).
These cells demonstrated perivascular distribution in a pseudorosette pattern with broad cytoplasmic processes radiating toward the centrally placed blood vessels (Figure 5).
Nodular hidradenomas also lack the uniform cells, "salt and pepper" chromatin, pseudorosette formation, and mucin production seen in EMPSGC.
Differentiating features for AIH from SLE-related liver disease are portal and periportal inflammation, piecemeal necrosis with dense lymphoid infiltrates, dominant portal tract plasma cell infiltration, hepatocyte pseudorosette formation whereas lupus-associated hepatitis shows predominantly lobular involvement with mild lobular inflammation and no piecemeal necrosis 19].
The cells ranged in size with scant and fragile cytoplasm, high nuclear/cytoplasmic ratios, hyperchromatic, angulated nuclei showing nuclear molding, focal pseudorosette formations, granular chromatin and inconspicuous nucleoli and some mitotic figures.
of Cases Percentage Poorly differentiated 15 35.7 Moderately differentiated 22 52.3 Well differentiated 5 11.9 Rosette Flexner-Wintersteiner 13 30.9 Pseudorosette 29 69.0 Microscopic Spread Optic nerve 16 38 Skeletal muscle 1 2.3 Lacrimal gland 2 4.7 Vascular emboli 2 4.7 Others Necrosis 34 80.9 Dystrophic calcification 11 26.1 Haemorrhage 10 23.8 Siderosis 4 9.5 Cholesterol slits 3 7.1 Basophilia 3 7.1
The distinguishing histologic characteristic is perivascular pseudorosette formation.
The spindle cells show pseudorosette around capillaries, scanty cytoplasm, mild pleomorphism and dense hyperchromatic nuclei.
Centrilobular canalicular cholestasis with acinar or pseudorosette formation is the predominant finding (Figure 8).
(1,2,4) Nuclear palisading around the stromal cores and pseudorosette formation around capillary vessels are also common features (Figure 1, A through D).
All 5 tumors consisted of an angiocentric growth pattern of bipolar spindle cells with slender nuclei that radiate from a central vessel to form pseudorosette structures (Figure 1, B).