Four different mechanisms have been described in the literature as causes of obstructive jaundice secondary to hepatobiliary tuberculosis: porta hepatis TB lymphadenitis causing extrinsic compression of the common bile duct [5, 8, 10-13], head of pancreas involvement mimicking a pseudoneoplasm
and obstructive the distal common bile duct [10, 14-18], a retroperitoneal mass caused by TB obstructing the distal bile duct , and a direct involvement of biliary epithelium or pericholangitis resulting in a single or multiple strictures mimicking cholangiocarcinoma [20-22].
The etiopathogenesis is still unknown, but several causes are hypothesized: Epstein-Barr virus association , red pulp abnormal transformation due to stromal proliferation, or hamartomas/ inflammatory pseudoneoplasm
final stage [6, 17].
In most circumstances, it is a misnomer because a mass actually exists, and hence, the term pseudoneoplasm would be more appropriate.
Furthermore, as more knowledge continues to accrue, the classification of pseudoneoplasms presented here will undoubtedly undergo revision.
While the pathogenesis of this entity is not well understood, CAT is a clinically important pseudoneoplasm because it often raises high suspicion for malignancy.
It is also germane to the topic of pseudoneoplasms because LHAS results from a developmental aberrancy and is not an acquired neoplasm (lipoma).
Inflammatory fibroid polyp is a rare mesenchymal pseudoneoplasm of the digestive system with unclear histogenesis.
Malakoplakia.--Malakoplakia is the best example of a pseudoneoplasm characterized by an eosinophilic cell infiltrate.
of the neuraxis (CPN) is a highly distinctive lesion of indeterminate nature.
or pseudotumor is defined in the medical dictionary as "a nonneoplastic enlargement that resembles a true neoplasm" or "a circumscribed fibrous exudate of inflammatory origin." This term encompasses a wide variety of morphologic abnormalities, with varying amounts of fibrosis and inflammation, which all have the propensity to mimic cancer clinically and histologically.
and hyperplasias of the dermis.
To the Editor.--We read the outstanding article by Miller and Tazelaar1 recently published in the Archives of Pathology & Laboratory Medicine about the main features of 5 cardiovascular pseudoneoplasms
(inflammatory myofibroblastic tumor, hamartoma of mature cardiac myocytes, mesothelial monocytic cardiac excrescences, calcified amorphous tumor, and lipomatous hypertrophy of the atrial septum).