Newcastle disease

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Newcastle disease

a viral disease of birds, including domestic fowl, characterized by respiratory and gastrointestinal or pneumonic and encephalitic symptoms; it is also transmissible to humans.

Newcastle disease

a serious paramyxovirus disease of poultry and other (including psittacine and passerine) birds. Clinical signs of Newcastle disease virus (NDV) include coughing, gasping and sneezing, diarrhea, petechiae, twisted neck, and paresis of legs and wings. Three strains exist: lentogenic, mesogenic, and velogenic, the last is the most pathogenic (mortality to 100%, may present with peracute signs or sudden death). In humans, velogenic strain may cause acute conjunctivitis and sometimes influenzalike symptoms persisting up to 3 weeks. Exotic disease in North America; first identified in California in fall 2002. Preventive measures include vaccination of poultry, quarantine, import restrictions, and banning feeding based on animal tissues.
[Newcastle-on-Tyne, England, where disease first reported]

New·cas·tle dis·ease

(nū'kas-ĕl di-zēz')
Conjunctivitis, eyelid edema, and inflammation caused by infection with an avian virus; recovery is usually spontaneous and takes 10-14 days.
[Newcastle-on-Tyne, England, where disease first reported]


a community in England near the location where Newcastle disease was first observed.
Newcastle disease - an influenzalike disease of birds that is transmissible to man if in contact with diseased birds. Synonym(s): avian influenza; Ranikhet disease


town in northern India.
Ranikhet disease - Synonym(s): Newcastle disease

Newcastle disease

an infectious, highly contagious disease of chickens, turkeys and many wild birds, occasionally infecting humans, caused by avian paramyxovirus-1, in the genus Avulavirus. The disease causes very heavy losses in birds of all ages and frequently occurs as massive outbreaks. There are a number of clinical forms of the disease, including a nervous form characterized by tremor, opisthotonos and paralysis, and a mortality rate of 90%, an acute respiratory form with high mortality, up to 90% in chickens, an acute respiratory form without significant death losses, and a clinically inapparent form. The disease is also classified, on epidemiological grounds, into velogenic (peracute), mesogenic (acute) and lentogenic (subacute) forms, which are caused by viruses with a corresponding variation in virulence. Called also avian pneumoencephalitis.