pseudoexfoliation


Also found in: Acronyms.

pseu·do·ex·fo·li·a·tion

(sū'dō-eks-fō'lē-ā'shŭn),
A condition simulating exfoliation in some respects, but in which the surface layer is not actually detached.

pseudoexfoliation (PXF) 

Deposition of greyish-white, flake-like basement membrane material on the anterior lens capsule, the iris and the ciliary processes with free-floating particles in the anterior chamber. It occurs mainly in the elderly. It often gives rise to glaucoma (pseudoexfoliation glaucoma). The origin of the pseudoexfoliative material is believed to be secondary to an abnormal basement membrane, produced by ageing epithelial cells in the eye, as well as in the skin and visceral organs. See pseudoexfoliation glaucoma; pseudoexfoliation syndrome.
References in periodicals archive ?
To find out the distribution of PCI in patients with Pseudoexfoliation (PXF) and to find out whether PCI can be taken as a predictor for clinical open angle glaucoma (OAG) secondary to pseudoexfoliation.
Exclusion criteria for all patients included a history of diabetes mellitus, systemic hypertension, glaucoma, pseudoexfoliation syndrome, chronic use of medicated eyedrops (antiglaucomatous, steroids, non-steroidal anti-inflammatory drugs, antibiotics, etc.
PEX was diagnosed by slit-lamp microscope investigation following mydriasis, provided that typical presence of a pseudoexfoliation component was found on the anterior lens capsule or the pupillary border.
According to Glaukos, the goal was to assess the long-term postoperative outcomes of one iStent implanted during cataract surgery in subjects with primary open-angle glaucoma, pseudoexfoliation glaucoma, secondary or post-traumatic glaucoma or ocular hypertension.
USPRwire, Mon Sep 21 2015] GlobalData's clinical trial report, "Pseudoexfoliation Syndrome Global Clinical Trials Review, H2, 2015" provides an overview of Pseudoexfoliation Syndrome clinical trials scenario.
Tissue inhibitor of metalloproteinase 4 in aqueous humor of patients with primary open angle glaucoma, pseudoexfoliation syndrome and pseudoexfoliative glaucoma and its role in proteolysis imbalance.
27 eyes had primary open angle glaucoma (POAG), 20 had glaucoma associated with the pseudoexfoliation syndrome, and 3 had pigmentary glaucoma.
Eyes with glaucoma, pseudoexfoliation, or prior ocular surgery were not selected for phacoemulsification during the course of the study.
They address pediatric cases, congenital subluxation of the crystalline lens, cataracts and glaucoma, pseudoexfoliation syndrome, phacoemulsifications with a small pupil, cataract surgery in age-related macular degeneration, brunescent cataract, and cataracts in high myopia, severe hyperopia, and retinitis pigmentosa.
Pseudoexfoliation glaucoma occurs when a whitish material, often found on all surfaces of the eye, causes clogging of the eye's drainage meshwork and increases the intraocular pressure.
1) A possible mechanism for the development of PEX and its subsequent progression to glaucoma may be the combination of clogging up of the trabeculum by pseudoexfoliation materials and/or pigments released from the iris, as well as trabecular endothelial dysfunction.
Pseudoexfoliation syndrome (PEXS) is an age-related disorder of the extracellular matrix and is frequently associated with severe chronic secondary open-angle glaucoma and cataract (1).