pseudobulbar affect


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Related to pseudobulbar affect: Pseudobulbar palsy

pseudobulbar affect

Abbreviation: PBA
The labile expression of emotions (as by pathological or inappropriate laughing or crying) out of proportion to the feelings experienced by the patient. PBA is characteristic of patients with amyotrophic lateral sclerosis, multiple sclerosis, and other brain diseases.
See also: affect
References in periodicals archive ?
Pseudobulbar affect: Prevalence and quality of life impact in movement disorders.
Validation of the CNS emotional lability scale for pseudobulbar affect (pathological laughing and crying) in multiple sclerosis patients.
Pseudobulbar affect: when patients laugh or cry, but don't know why.
Less frequently, people with MS may have pseudobulbar affect (PBA), a condition that can produce uncontrollable laughing or crying spells that are out of proportion to or disconnected from what people are feeling.
Biopharmaceutical company Avanir Pharmaceuticals Inc (NasdaqGS:AVNR) stated on Tuesday that NUEDEXTA (dextromethorphan hydrobromide/quinidine sulfate) has been granted approval in the European Union for the treatment of pseudobulbar affect (PBA), irrespective of underlying neurologic disease or injury.
A Your father's behavior may well be symptomatic of a neurological condition called pseudobulbar affect (PBA).
A combination of dextromethorphan hydrobromide and quinidine sulfate recently became the first treatment to be approved by the Food and Drug Administration for the treatment of pseudobulbar affect, based on a study of patients with amyotrophic lateral sclerosis and multiple sclerosis.
Patients were given a test measuring how often they laughed or cried unintentionally due to a neural disorder known as pseudobulbar affect. Those taking Zenvia reported fewer episodes of involuntary laughing and crying when asked to rank their symptoms' severity, according to a study presented last week in Toronto at the American Academy of Neurology's annual meeting.
(5-7) Affective disorders, such as euphoria and pseudobulbar affect, are less common, but are found in up to about 10% of patients during the course of illness.
A double-blind, placebo-controlled, multicenter study to assess the safety and efficacy of AVP-923 (dextromethorphan/quinidine) in the treatment of pseudobulbar affect in patients with multiple sclerosis [Abstract].
Serotonin, fluoxetine and pseudobulbar affect. Neurology.