: Prevalence and quality of life impact in movement disorders.
Validation of the CNS emotional lability scale for pseudobulbar affect
(pathological laughing and crying) in multiple sclerosis patients.
: when patients laugh or cry, but don't know why.
Less frequently, people with MS may have pseudobulbar affect
(PBA), a condition that can produce uncontrollable laughing or crying spells that are out of proportion to or disconnected from what people are feeling.
Biopharmaceutical company Avanir Pharmaceuticals Inc (NasdaqGS:AVNR) stated on Tuesday that NUEDEXTA (dextromethorphan hydrobromide/quinidine sulfate) has been granted approval in the European Union for the treatment of pseudobulbar affect
(PBA), irrespective of underlying neurologic disease or injury.
A Your father's behavior may well be symptomatic of a neurological condition called pseudobulbar affect
A combination of dextromethorphan hydrobromide and quinidine sulfate recently became the first treatment to be approved by the Food and Drug Administration for the treatment of pseudobulbar affect
, based on a study of patients with amyotrophic lateral sclerosis and multiple sclerosis.
Patients were given a test measuring how often they laughed or cried unintentionally due to a neural disorder known as pseudobulbar affect
. Those taking Zenvia reported fewer episodes of involuntary laughing and crying when asked to rank their symptoms' severity, according to a study presented last week in Toronto at the American Academy of Neurology's annual meeting.
(5-7) Affective disorders, such as euphoria and pseudobulbar affect
, are less common, but are found in up to about 10% of patients during the course of illness.
A double-blind, placebo-controlled, multicenter study to assess the safety and efficacy of AVP-923 (dextromethorphan/quinidine) in the treatment of pseudobulbar affect
in patients with multiple sclerosis [Abstract].
Serotonin, fluoxetine and pseudobulbar affect