pseudoallergy

pseudoallergy

An adverse, nonimmunologic, anaphylaxis-like reaction of sudden onset which is associated with food ingestion; pseudoallergies may be caused by an anaphylactoid reaction, intolerance (e.g., psychogenic response), metabolic defect (e.g., enzymatic deficiency, tyramine reaction) and toxicity (e.g., tetrodotoxin).
 
True allergies to foods are hypersensitivity reactions caused by mast cell release of histamines evoked by IgE, which is most commonly linked to eggs, milk, peanuts, nuts, fish, soy beans and shrimp.

pseudoallergy

Clinical immunology A nonimmunologic, anaphylaxis-like reaction of sudden onset, associated with food ingestion; PAs may be due to an anaphylactoid reaction, intolerance–eg, psychogenic response, metabolic defect–eg, enzymatic deficiency, tyramine reaction, or toxicity–eg, tetrodotoxin. See Cheese reaction, Food allergy, Food intolerance. Cf Allergy.

pseudoallergy

(sood″ō-al′ĕr-jē) [ pseudo- + allergy]
An allergic-like reaction such as an outbreak of hives that is not caused by activation of the immune system. Some instances are attributable to exposure to food colorings or preservatives.
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References in periodicals archive ?
Szebeni, "Complement activation-related pseudoallergy: a new class of drug-induced acute immune toxicity," Toxicology, vol.
Szebeni, "Complement activation-related pseudoallergy: a stress reaction in blood triggered by nanomedicines and biologicals," Molecular Immunology, vol.
Pseudoallergy may be the most likely mechanism for our patient's colistin-induced angio-oedema.
Additionally, the complement activation triggers a cascade of inflammatory and adverse complex reactions, named complement activation-related pseudoallergy (CARPA), that reflect in symptoms of transient cardiopulmonary distress.
I also hit the Internet for information and came across a report on benzoic acid and sodium benzoate by IPCS (International Programme on Chemical Safety) at inchem.org which stated "benzoates at lower doses can cause non-immunological contact reactions (pseudoallergy) in sensitive persons."