Itraconazole is the drug of choice for uncommon IFI like mild/moderate coccidioidomycosis, paracoccidioidomycosis, histoplasmosis, blastomycosis, sporotrichosis, and pseudallescheriasis. Some studies show that it may be used for mild aspergillosis disease.
Voriconazole is the preferred therapy for aspergillosis, scedosporiosis, fusariosis, and pseudallescheriasis and alternative therapy for candidiasis.
Here, we are reporting an unusual case of invasive pulmonary pseudallescheriasis
in an immunocompetent host in association with a long term history of occupational exposure to cow dung .
Produce sintomatologia clinica que se agrupa bajo los terminos de pseudallescheriasis
o scedosporiasis: produce en personas inmunocompetentes lesiones localizadas (micetoma) y en inmunosuprimidos, enfermedad invasiva: la forma pulmonar invasiva es similar a la aspergilosis.
Voriconazole is reported to be effective in pulmonary pseudallescheriasis (18).
Case of pulmonary pseudallescheriasis responding successfully to treatment with voriconazole.
Pseudallescheria boydii brain abscess successfully treated with voriconazole and surgical drainage: case report and literature review of central nervous system pseudallescheriasis
. Clin Infect Dis.
as an Aggressive Opportunistic Infection in a Bone Marrow Transplant Recipient--Nonaka et al) Answers to this month's questions: 1, False.
However, an increasing number of cases of disseminated pseudallescheriasis has been observed in immunocompromised patients due to increased incidence of human immunodeficiency virus infection, antineoplastic or immunosuppressive medication, and bone marrow or solid organ transplantation.
However, the use of corticosteroids, immunosuppressive or antineoplastic medication, bone marrow or solid organ transplantation, and human immunodeficiency virus infection have increased the occurrence of disseminated pseudallescheriasis. (3,4,6,7) The portal of entry could be lung, paranasal sinuses, or skin by traumatic inoculation.