psammoma bodies


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psam·mo·ma bod·ies

1. mineralized bodies occurring in the meninges, choroid plexus, and in certain meningiomas; composed usually of a central capillary surrounded by concentric whorls of meningocytes in various stages of hyaline change and mineralization; can also occur in benign and malignant epithelial tumors (such as papillary ovarian or thyroid carcinoma); Synonym(s): sand bodies
2. Synonym(s): corpora arenacea
3. Synonym(s): calcospherite

psam·mo·ma bod·ies

(sa-mō'mă bod'ēz)
1. Mineralized bodies occurring in the meninges, choroid plexus, and in some meningiomas; usually composed of a central capillary surrounded by concentric whorls of meningocytes in various stages of hyaline change and mineralization; can also occur in benign and malignant epithelial tumors (often papillary) or with chronic inflammation;
2. Synonym(s): corpora arenacea.
3. Synonym(s): calcospherite.
References in periodicals archive ?
Calcifications are basophilic in centre surrounding eosinophilic border resembling psammoma bodies.
It was considered to be an encapsulated variant of papillary carcinoma due to similar nuclear features, presence of psammoma bodies, immunohistochemistry profile and RET/PTC translocation.
3) PRCC CCPRCC Morphology Architecture Papillary Papillary, tubulocystic Cytology Basophilic or Clear eosinophilic Nuclear grade Low-high Low Helpful features Psammoma bodies, Subnuclear foamy macrophages vacuoles Immunohistochemistry AMACR + -- CD10 + -- CK7 + + RCC Ma + -- Molecular Chromosomal gains 7, 12, 16, Variable, 17, 20 limited data Chromosomal losses Y Abbreviations: AMACR, [alpha]-methyl-acyl-coenzyme A;CCPRCC, clear cell papillary renal cell carcinoma; CCRCC, clear cell renal cell carcinoma; CK7, cytokeratin 7;PRCC, papillary renal cell carcinoma; RCC Ma, renal cell carcinoma marker; VHL, von Hippel-Lindau; +, positive expression of marker; -, no expression of marker.
Caption: Figure 3: Microscopically, diffusely scattered tumor aggregates, extensive fibrosis, marked lymphocytic infiltration with formation of lymphoid follicles, and abundant psammoma bodies (a) were evident against a background of Hashimoto's thyroiditis (b) (Hematoxylin & Eosin stain x40).
6) Concentric calcified deposits (Liesegang rings) that resemble psammoma bodies are formed in the amyloid material.
Nuclear pseudoinclusions and psammoma bodies, which are characteristic histologic features of meningiomas, are not observed in HPCs.
6,11 Frequent calcifications in the form of psammoma bodies or dystrophic calcification may be present.
A pathologist reported that the tissue was a benign serous papillary rumor with psammoma bodies.
The stroma presented fibroblastic reaction and were accompanied by psammoma bodies.
The presence of psammoma bodies in a cervical cytology smear has long been thought to be associated with gynecologic malignancies, but a retrospective review of 400,000 smears collected during routine screening suggests they may be an incidental finding in an asymptomatic population.
As gynecologists, we worry about psammoma bodies, because they are frequently associated with ovarian serous papillary carcinomas as well as other .
malignancies," he said at the annual meeting of the Pacific Coast Obstetrical and Gynecological Society But studies that linked 60% of smears containing psammoma bodies to cancer generally included samples from women with malignant background cytology or abnormal symptoms such as postmenopausal bleeding, he noted.