prozone(redirected from prozone reaction)
in an agglutination or precipitation reaction, the zone of relatively high antibody concentrations within which no reaction occurs. As the antibody concentration is lowered below the prozone, the reaction occurs. This phenomenon may be due simply to antibody excess or it may be due to blocking antibody or to nonspecific inhibitors in serum.
In the case of agglutination and of precipitation, the phenomenon in which visible reaction does not occur in mixtures of specific antigen and antibody because of antibody excess.
A phenomenon in which visible agglutination and precipitation do not occur in mixtures of specific antigen and antibody because of antibody excess.