prozone

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prozone

[pro´zōn]

in an agglutination or precipitation reaction, the zone of relatively high antibody concentrations within which no reaction occurs. As the antibody concentration is lowered below the prozone, the reaction occurs. This phenomenon may be due simply to antibody excess or it may be due to blocking antibody or to nonspecific inhibitors in serum.

pro·zone

(prō'zōn),

In the case of agglutination and of precipitation, the phenomenon in which visible reaction does not occur in mixtures of specific antigen and antibody because of antibody excess.

Synonym(s): prezone

prozone

/pro·zone/ (pro´zōn) the phenomenon exhibited by some sera, in which agglutination or precipitation occurs at higher dilution ranges, but is not visible at lower dilutions or when undiluted.

pro·zone

(prō'zōn)

A phenomenon in which visible agglutination and precipitation do not occur in mixtures of specific antigen and antibody because of antibody excess.

prozone

the phenomenon exhibited by some sera, in which agglutination or precipitation occurs at higher dilution ranges, but is not visible at lower dilutions or when undiluted.

Mentioned in ?

antibody excess

References in periodicals archive ?

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