prozone

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prozone

[pro´zōn]

in an agglutination or precipitation reaction, the zone of relatively high antibody concentrations within which no reaction occurs. As the antibody concentration is lowered below the prozone, the reaction occurs. This phenomenon may be due simply to antibody excess or it may be due to blocking antibody or to nonspecific inhibitors in serum.

pro·zone

(prō'zōn),

In the case of agglutination and of precipitation, the phenomenon in which visible reaction does not occur in mixtures of specific antigen and antibody because of antibody excess.

Synonym(s): prezone

Farlex Partner Medical Dictionary © Farlex 2012

pro·zone

(prō'zōn)

A phenomenon in which visible agglutination and precipitation do not occur in mixtures of specific antigen and antibody because of antibody excess.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

Mentioned in ?

antibody excess

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Other interferences such as the prozone effect and the volume displacement effect are discussed below.