provirus

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Related to proviruses: proviral

provirus

 [pro-vi´rus]
a DNA transcript of an RNA virus that migrates from the cytoplasm into the nucleus and integrates into the host genome by crossing over so that it will be thus replicated in the daughter cells.

pro·vi·rus

(prō-vī'rŭs),
The precursor of an animal virus, usually a retrovirus; theoretically analogous to the prophage in bacteria, the provirus is integrated in the nucleus of infected cells and can be activated in response to certain stimuli.

provirus

/pro·vi·rus/ (pro-vi´rus) the genome of an animal virus integrated (by crossing over) into the chromosome of the host cell, and thus replicated in all of its daughter cells. It can be activated to produce a complete virus; it can also cause transformation of the host cell.

provirus

(prō′vī′rəs, prō-vī′-)
n. pl. provi·ruses
A form of a virus that allows it to be integrated into the genome of a host cell and to replicate in concert with the cell's genetic material without causing cell lysis.

pro′vi′ral (-rəl) adj.

provirus

[-vī′rəs]
a stage of viral replication in which the viral genetic information has been integrated into the genome of the host cell. It may be activated spontaneously or by a specific stimulus to direct the cell to produce new virions to progress to a complete virus.

pro·vi·rus

(prō-vī'rŭs)
The precursor of an animal virus; theoretically analogous to the prophage in bacteria, the provirus being integrated into the nucleus of infected cells.

provirus

the DNA of a VIRUS that has integrated into the DNA of the host CELL and is transmitted from one cell generation to the next in this state. No infective virus particles are produced. The provirus can excise from the host's DNA and resume a productive viral cycle with the production of virus particles.

pro·vi·rus

(prō-vī'rŭs)
The precursor of an animal virus; theoretically analogous to the prophage in bacteria, the provirus being integrated into the nucleus of infected cells.

provirus

the genome of an animal virus integrated into the chromosome of the host cell, and thus transferred to in all of its daughter cells.
References in periodicals archive ?
Study results showed that among 213 HIV proviruses isolated from the reservoirs of eight patients and initially unresponsive to highly potent biological stimuli, some 12 percent could later still become active, and were capable of replicating their genetic material and transmitting infection to other cells.
The study found that the average frequency of intact non-induced proviruses was "at least 60-fold higher" than the potentially dangerous latent viruses that scientists already knew about.
type B/D viruses in sheep and goats reveals numerous proviruses.
Scientists from Tokyo-based Nihon University highlight the fact that latently infected cells harbour HIV-1 proviral DNA genomes integrated with heterochromatins, allowing for the persistence of transcriptionally silent proviruses.
EAV are also present in line-0 chickens (ev-negative), which have been bred to have no ev proviruses (12).
The researchers are now adapting this system to detect latent HIV proviruses, which remains dormant in some infected cells even after treatment.