provirus

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provirus

 [pro-vi´rus]
a DNA transcript of an RNA virus that migrates from the cytoplasm into the nucleus and integrates into the host genome by crossing over so that it will be thus replicated in the daughter cells.

pro·vi·rus

(prō-vī'rŭs),
The precursor of an animal virus, usually a retrovirus; theoretically analogous to the prophage in bacteria, the provirus is integrated in the nucleus of infected cells and can be activated in response to certain stimuli.

provirus

(prō′vī′rəs, prō-vī′-)
n. pl. provi·ruses
A form of a virus that allows it to be integrated into the genome of a host cell and to replicate in concert with the cell's genetic material without causing cell lysis.

pro′vi′ral (-rəl) adj.

pro·vi·rus

(prō-vī'rŭs)
The precursor of an animal virus; theoretically analogous to the prophage in bacteria, the provirus being integrated into the nucleus of infected cells.

provirus

the DNA of a VIRUS that has integrated into the DNA of the host CELL and is transmitted from one cell generation to the next in this state. No infective virus particles are produced. The provirus can excise from the host's DNA and resume a productive viral cycle with the production of virus particles.

pro·vi·rus

(prō-vī'rŭs)
The precursor of an animal virus; theoretically analogous to the prophage in bacteria, the provirus being integrated into the nucleus of infected cells.
References in periodicals archive ?
All 10 men had asymptomatic HTLV-1 infections, but 2 men had a high proviral load (>1%), which places them at risk for HTLV-associated disease.
(34) Herein, we confirmed that patients with KCS had significantly higher HTLV-1 proviral load than patients without the disease, regardless the presence of HAM/TSP.
The behavior of the virus in the intracellular environment is variable, because it can remain in a state called quiescence, when the proviral DNA, even if integrated with the cellular DNA, has not been activated and is; therefore, not multiplying, or the DNA can be inside the cell but not integrated (CAVALCANTE et al., 2013; BLACKLAWS, 2012; CRUZ et al., 2013).
The search criteria were not restricted to the LTR regions of the proviral HIV genome, but were instead applied to the entire proviral HIV genome.
Kopp, "Focal glomerulosclerosis in proviral and c-fms transgenic mice links Vpr expression to HIV-associated nephropathy," Virology, vol.
Interrupting this locus with the proviral beta geo reporter gene led to ubiquitous expression of beta-galactosidase, suggesting that the Rosa26 locus encodes universally expressed lncRNAs in mice [99].
Moreover, they found that effective excision of LTR could clear full-length HIV-1 proviral DNA.
Sodroski, Harvard University, Boston) which contains the complete proviral genome of the HIV-1 HXBc2 ([vif.sup.+]-[vpu.sup.-]-v[pr.sup.-]-[nef.sup.-]) (Ratner et al., 1985), by inserting the Vpu, Vpr and Nef encoding sequences and deleting the BglII-BglII env region.
Rap id detection of HIV-1 proviral DNA for early infant diagnosis using recombinase polymerase amplification.