provirus

(redirected from proviral)
Also found in: Dictionary, Thesaurus, Encyclopedia.

provirus

 [pro-vi´rus]
a DNA transcript of an RNA virus that migrates from the cytoplasm into the nucleus and integrates into the host genome by crossing over so that it will be thus replicated in the daughter cells.

pro·vi·rus

(prō-vī'rŭs),
The precursor of an animal virus, usually a retrovirus; theoretically analogous to the prophage in bacteria, the provirus is integrated in the nucleus of infected cells and can be activated in response to certain stimuli.

provirus

/pro·vi·rus/ (pro-vi´rus) the genome of an animal virus integrated (by crossing over) into the chromosome of the host cell, and thus replicated in all of its daughter cells. It can be activated to produce a complete virus; it can also cause transformation of the host cell.

provirus

(prō′vī′rəs, prō-vī′-)
n. pl. provi·ruses
A form of a virus that allows it to be integrated into the genome of a host cell and to replicate in concert with the cell's genetic material without causing cell lysis.

pro′vi′ral (-rəl) adj.

provirus

[-vī′rəs]
a stage of viral replication in which the viral genetic information has been integrated into the genome of the host cell. It may be activated spontaneously or by a specific stimulus to direct the cell to produce new virions to progress to a complete virus.

pro·vi·rus

(prō-vī'rŭs)
The precursor of an animal virus; theoretically analogous to the prophage in bacteria, the provirus being integrated into the nucleus of infected cells.

provirus

the DNA of a VIRUS that has integrated into the DNA of the host CELL and is transmitted from one cell generation to the next in this state. No infective virus particles are produced. The provirus can excise from the host's DNA and resume a productive viral cycle with the production of virus particles.

pro·vi·rus

(prō-vī'rŭs)
The precursor of an animal virus; theoretically analogous to the prophage in bacteria, the provirus being integrated into the nucleus of infected cells.

provirus (prōvī´rus),

n a type of virus incorporated into a host cell's genetic material that transmits from one generation of cells to the next via cell replication without triggering the separation or decomposition of the cell.

provirus

the genome of an animal virus integrated into the chromosome of the host cell, and thus transferred to in all of its daughter cells.
References in periodicals archive ?
This suggests that proviral silencing is controlled by coordinated mechanisms involving multiple cellular pathways.
The primers used to n-PCR for detection of proviral BLV DNA.
Distribucion de frecuencias alelicas del gen boladrb3 en animales blv(-) y blv(+) de baja carga proviral, pertenecientes a un rodeo comercial de raza Holstein y Holstein x Jersey.
Investigation of the bovine leukemia virus proviral DNA in human leukemia and lung cancers in Korea.
Se han identificado dos mecanismos de resistencia: por mutaciones que permiten que la transcriptasa reversa (TR) discrimine entre un INTR y un dNTP producido naturalmente por la celula, previniendo asi que los INTR sean incorporados en la cadena creciente de ADN viral; y por mutaciones que median la escision dependiente de ATP del INTR que ya se encuentra incorporado a la cadena creciente de ADN, permitiendo que la enzima reinicie la sintesis del ADN proviral.
En el ADN proviral aparecen las repeticiones terminales largas (LTR, "Long Terminal Repeats"), largas secuencias repetidas a ambos extremos que juegan un papel crucial en la transcripcion.
HIV's genetic blueprint, known as proviral DNA, can lie dormant for years or even decades within a host cell's chromosomes, ready to produce new virus when the cell is activated
La presencia de anticuerpos contra el HTLV-1 en sangre y liquido cefalorraquideo se confirma a traves de ELISA y Western blot (1,4), mientras que el ADN proviral de los linfocitos se detecta mediante tecnicas de PCR (1).
The frequency of CD127 low expressing CD4+CD25 high T regulatory cells is inversely correlated with human T lymphotrophic virus type-1 (HTLV-I) proviral load in HTLV-I-infection and HTLV-I-associated myelopathy/tropical spastic paraparesis.
Analisis para detectar secuencias del virus del VIH integradas en el ADN proviral de las celulas mononucleares perifericas del paciente (AI).
El ADN proviral es integrado posteriormente al genoma de la celula infectada mediante la accion de la enzima integrasa, y este podra ser posteriormente transcrito a ARN viral nuevo que sera traducido con la participacion de la proteasa.