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in the clotting of blood, also known as: proaccelerin (Owren), labile or plasma labile factor (Quick), plasma accelerator globulin (Ware and Seegars), thrombogene (Nolf), prothrombokinase (Milstone), plasmin prothrombins conversion factor (Stefanini), component A of prothrombin (Quick), prothrombin accelerator (Fantl and Nance), cofactor of thromboplastin (Honorato), and accelerator factor. Factor V does not have enzymatic action itself but participates in the common pathway of coagulation by binding factor Xa to platelet surfaces. Deficiency of this factor leads to a rare hemorrhagic tendency known as parahemophilia or hypoproaccelerinemia, with autosomal recessive inheritance; those who are heterozygous are recognized by reduced levels of factor V but have no bleeding tendency.
In blood clotting, it does not have enzymatic action itself but participates in the common pathway of coagulation by binding factor Xa to platelet surfaces.
In blood clotting, it participates in the clotting of the blood by forming a complex with factor IXa, platelets, and calcium and by enzymatically catalyzing the activation of factor X.
n See factor VIII.