falciparum cultures a 5.5-fold increase in a gene encoding an ubiquitin-specific protease and a 5.5-fold increase in a gene encoding a proteosome
subunit a were observed .
She and her colleagues have discovered a way to take advantage of the proteosome
The researchers wanted to see if they could find a molecule that inhibited Usp14, thus allowing the proteosome
to work effectively.
Future prospective studies should focus on the use of adjuvant chemotherapy and/or novel therapeutic agents, i.e., proteosome
(6) New agents called proteosome
inhibitors are very promising induction therapy agents, but they are currently still under investigation in various clinical trials as first-line therapy.
In the absence of functional Cosmc, core 1 [beta]3-Gal-T is degraded in the proteosome
The primary aim of this work is to develop a sub-unit plague vaccine using a recombinant plague antigen, the FIV protein, formulated with the Proteosome
ID Biomedical (Vancouver, Canada) received an official Notice of Allowance from the United States Patent and Trademark Office with respect to its patent application entitled, "Proteosome
Among the mRNAs of particular interest are homologues of sec6l (accession number BC019158), proteosome
protein (BC003197), calmodulin-2 (NM_001743) and epsilon-container (AB042117), all proteins with potential function in membrane biogenesis.
degradation of cyclin-dependent kinase inhibitor p27 is associated with a decreased overall survival in mantle cell lymphoma.
NF-[kappa]B inhibitors, including pyrrolidine dithiocarbamate , parthenolide , gliotoxin , and proteosome
inhibitor , were reported to cause GSH depletion.
[p27.sup.Kip1] is regulated by p90 RSK and, once phosphorylated, is translocated to the cytosol, followed by ubiquitination and degradation by the proteosome
, allowing progression to S-phase .