proteomics


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proteomics

(prō-tē-om'iks),
The identification and study of the proteins of a cell, tissue, or organism to determine their three-dimensional structure and to map their interactive networks to discover their function and the structure of drugs with the potential to interact in a therapeutic way with disease-associated proteins; goal is not only formulation of new drugs but also diagnostics and determining the presence of or absence of specific proteins associated with a disease or health.
See also: proteome, proteome image.

proteomics

(prō′tē-ō′mĭks)
n.
(used with a sing. verb) The analysis of the expression, localizations, functions, and interactions of the proteins expressed by the genetic material of an organism.

proteomics

The study of the proteome-the proteins expressed by the approximately 22,000 genes in the GENOME or by a cell. The form and quantity of the proteins produced by a cell cannot be fully predicted from DNA or RNA analysis alone. This is because of the controls and the many modifications that can occur in the stages between transcription and protein formation. Thus the totality of the genes can result in at least several hundred thousand different proteins. Proteomics includes the study of the factors that cause this multiplication. The discipline is being applied effectively to cancer studies.

proteomics

characterization of the PROTEOME by cataloguing and analysing the proteins. This involves:
  1. (a) identifying each protein in the proteome;
  2. (b) determining the sequence (see AMINO-ACID SEQUENCE of the proteins and constructing a database;
  3. (c) determining the amount of protein in different cell types and at different stages of development and
  4. (d) investigating the interactions between proteins.
References in periodicals archive ?
The program is a joint translational medicine project aimed at moving proteomics from the research laboratory into clinical practice.
Proteomics also offers potential for tailoring therapy to render it more effective.
-- Obtain remote systems management for Glaucus Proteomics' in-house computing needs.
These and other technological developments contribute to the feasibility of the large-scale analyses that proteomics has set out to tackle.
The FLEX CHIP(TM) System also offers other key applications for the proteomics and drug discovery markets.
Myriad Proteomics will be capitalized at $164 million and will be owned 50% by Myriad Genetics Inc., a biopharmaceutical venture business in Utah.
Proteome Systems chief executive officer and founder Keith Williams says his company is keen to develop a range of products that will support protein analysis and pioneer the commercialisation applications of proteomics.
Proteomics: quantitative and physical mapping of cellular proteins.
M2 PRESSWIRE-July 31, 2019-: Proteomics Technologies, Markets and Companies Research Report 2019: Largest Expansion will be in Bioinformatics and Protein Biochip Technologies
Philadelphia, PA, June 3, 2019 - (ACN Newswire) - Proteomics International (PILL; ASX: PIQ) will be at the 2019 BIO International Convention in Philadelphia (stand #2349) preparing for the US roll-out of PromarkerD, a blood test that can diagnose and predict whether a healthy patient will develop diabetic kidney disease.