proteomics

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Related to proteomic: Metabolomics

proteomics

(prō-tē-om'iks),
The identification and study of the proteins of a cell, tissue, or organism to determine their three-dimensional structure and to map their interactive networks to discover their function and the structure of drugs with the potential to interact in a therapeutic way with disease-associated proteins; goal is not only formulation of new drugs but also diagnostics and determining the presence of or absence of specific proteins associated with a disease or health.
See also: proteome, proteome image.

proteomics

(prō′tē-ō′mĭks)
n.
(used with a sing. verb) The analysis of the expression, localizations, functions, and interactions of the proteins expressed by the genetic material of an organism.

proteomics

The study of the proteome-the proteins expressed by the approximately 22,000 genes in the GENOME or by a cell. The form and quantity of the proteins produced by a cell cannot be fully predicted from DNA or RNA analysis alone. This is because of the controls and the many modifications that can occur in the stages between transcription and protein formation. Thus the totality of the genes can result in at least several hundred thousand different proteins. Proteomics includes the study of the factors that cause this multiplication. The discipline is being applied effectively to cancer studies.

proteomics

characterization of the PROTEOME by cataloguing and analysing the proteins. This involves:
  1. (a) identifying each protein in the proteome;
  2. (b) determining the sequence (see AMINO-ACID SEQUENCE of the proteins and constructing a database;
  3. (c) determining the amount of protein in different cell types and at different stages of development and
  4. (d) investigating the interactions between proteins.
References in periodicals archive ?
M2 PRESSWIRE-July 31, 2019-: Proteomics Technologies, Markets and Companies Research Report 2019: Largest Expansion will be in Bioinformatics and Protein Biochip Technologies
Human spermatozoa can provide optimal cells to be investigated from a proteomic perspective because they do not represent physiologically active transcription and translation.
A third iteration of CPTAC now integrates Proteomic Characterization Centers--which are tasked with the analysis of five new cancer types and the development of a minimum of 1,000 targeted assays; Proteogenomic Data Analysis Centers--which develop and apply novel approaches for extracting maximal information from proteogenomic data; and Proteogenomic Translational Research Centers--which apply proteogenomic analyses to samples obtained from patients participating in active NCI-sponsored clinical trials.
What is the additional information that proteogenomics can offer compared to either genomic or proteomic platforms?
Biotech Support Group LLC is a leading provider of proteomic, metabolomic and genomic sample preparation and enrichment products and services.
The basic premise of next-generation companion diagnostics is the use of an FDA-approved drug/biomarker combination based on a cancer's genomic and proteomic profile assessed on high-throughput platforms such as NGS and MS proteomics.
Yajnavalka Banerjee said that the team aims to obtain an insight into the venoms of these nine species through diverse proteomic and suitable molecular biology techniques, which could lead to the identification of drug leads targeting some common human diseases.
Schuster investigates how patent law institutions, in particular patent offices, currently treat proteomic inventions, and how they would treat the range of inventions, primarily pharmaceuticals, that can be expected to materialize in the near future.
* Use of proteomic technologies in the drug development pipeline