proteolipid

proteolipid

 [pro″te-o-lip´id]
a combination of a peptide or protein with a lipid, having the solubility characteristics of lipids.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

proteolipid

(prō″tē-ō-lĭp′ĭd)
A lipid-protein complex that is insoluble in water. It is found principally in the brain.
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
The most important protein components of the myelin that target the immune system include myelin basic protein, myelin-associated glycoprotein, protein proteolipid protein, and myelin oligodendrocyte glycoprotein.
found ADEM to be characterized by IgG autoantibodies targeting myelin basic protein, proteolipid protein, myelin-associated oligodendrocyte basic glycoprotein and alpha-B-crystallin, whereas MS was characterized by IgM autoantibodies targeting myelin basic protein, proteolipid protein, myelin-associated oligodendrocyte basic glycoprotein, and oligodendrocyte specific protein.
It is reported that a numerous neuroendocrine self-antigens are expressed by the thymic epithelium which is controlled by the autoimmune regulator (AIRE) gene/protein.[18] According to a review, numerous gens are expressed in the thymus, including circulatory, central nervous, digestive, and eyes.[19] Myelin basic protein (MBP) is the second most abundant protein after proteolipid protein (PLP) in CNS.
PLP1 is further translated into the proteolipid protein 1 (PLP1), a 276 aminoacid peptide, or the isoform called DM20, which loses 35 residues inside its intracellular loop.
This dependency has been demonstrated in mice deficient in the myelin-specific proteolipid protein (PLP/DM20).
Pascual, "Bystander-mediated stimulation of proteolipid protein-specific regulatory T (Treg) cells confers protection against experimental autoimmune encephalomyelitis (EAE) via TGF-[beta]," Journal of Neuroimmunology, vol.
Proteolipid protein (PLP) peptide (p)139-151, corresponding to the mouse sequence (HSLGKWLGHPDKF) was synthesized on a peptide synthesizer and purified by HPLC.
SSC, Sus scrofa chromosome, AR, androgen receptor, PGK1, phosphoglycerate kinase 1, PLP1, proteolipid protein 1, tBg, thyroxine-binding globulin, CAPN6, calpain 6.
The persistency of these conditions would bring to supercomplex disaggregation and alteration of the mitochondrial proteolipid arrangement.
The most common cause of PMD is a mutation of the Proteolipid protein (PLP) gene producing a structural protein involved in the construction of central nervous system myelin [3-6].
(1994) Glial cell degeneration and hypomyelination caused by overexpression of myelin proteolipid protein gene.
Pelizaeus Merzbacher's Disease (PMD) also called leukodystrophy hypomyelinating 1 (HDL1) is an inherited allelic leukodystrophy caused by mutations of the proteolipid protein 1 gene (PLP1).