Caption: An image of the proteoglycans
that have increased in the perineuronal net (green) that surrounds nerve cells (red) in the spinal cord following injury.
Despite the significance of the mechanism which we found in our current study, the final outcome of ROS and Nox inhibition should also be determined on TGF-[beta] target genes such as proteoglycans
The basement membrane proteoglycans
, namely a large agrin-LP (CGI_10007223) and heparan sulfate proteoglycan
(perlecan-LP, CGI_10025660), are expressed differently from other genes in oyster development.
Dean, "The macromolecular characteristics of cartilage proteoglycans
do not change when synthesis is up-regulated by link protein peptide," Biochimica et Biophysica Acta (BBA) - General Subjects, vol.
Intermediate filament of nucleus pulposus cells is composed of type II collagen, proteoglycan
, and Cytokeratin 8 protein .
Gottschall, "Lectican proteoglycans
, their cleaving metalloproteinases, and plasticity in the central nervous system extracellular microenvironment," Neuroscience, vol.
Chakravarti, "The small leucine-rich repeat proteoglycans
in tissue repair and atherosclerosis," Journal of Internal Medicine, vol.
Histological changes of chondroitin sulfate proteoglycans
(CSPGs), tenascin C, and collagen IV in the 10- and 20-day gliomas by immunohistochemistry.
They were then processed according to routine procedures and the slides were stained with hematoxylin and eosin (H&E) and Safranin O fast green to evaluate the concentration of proteoglycans
. They were assessed by 2 independent observers in a blind study using the criteria established by MANKIN et al.
Dynamic ECMs form the microenvironment around cells and are composed of collagens, glycoproteins, glycosaminoglycans (GAGs), and proteoglycans
Homozygous mutations in the PAPSS2 gene lead to impaired sulfation of proteoglycans
and cause spondyloepimetaphyseal dysplasia (SEMD) Pakistani type which is characterized by short stature, short bowed legs, platyspondyly, narrow intervertebral spaces, short femoral neck, irregular metaphyses, and epiphyses.
It is covalently attached on several core proteins creating a variety of proteoglycans
(PGs) found in the extracellular matrix (ECM) and cell membrane, but also intracellularly (Elgawish et al., 2015).