proteinase(redirected from proteinase resistant protein (prp))
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any peptidase that catalyzes the cleavage of internal bonds in a polypeptide or protein. Inhibition of the action of endopeptidases (proteases) in viruses causes formation of noninfectious particles; certain antiviral drugs work in this way (see protease inhibitors). Called also protease and proteinase.
An enzyme that catalyzes the hydrolysis of a peptide chain at points well within the chain, not near either terminus; for example, pepsin, trypsin. Compare: exopeptidase.
proteinase/pro·tein·ase/ (pro´tēn-ās″) endopeptidase.
proteinase(prōt′n-ās′, -āz′, prō′tē-nās′, -nāz′)
An endopeptidase, such as pepsin, trypsin, or papain.
Etymology: Gk, proteios, first rank, ase, enzyme suffix
a proteolytic enzyme that splits protein molecules at central linkages. Also called tryptase.
protease; proteinase enzyme that breaks down/proteolyses protein
any enzyme that catalyzes the splitting of interior peptide bonds in a protein; an endopeptidase.
proteinase resistant protein (prp)
a protein which resists digestion by proteinases; the amyloid fibrils in brain tissue of sheep affected with scrapie contain such a prp.