protein-bound iodine


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iodine

 (I) [i´o-dīn]
a chemical element, atomic number 53, atomic weight 126.904. (See Appendix 6.) Iodine is essential in nutrition, being especially prevalent in the colloid of the thyroid gland. It is used in the treatment of hypothyroidism and as a topical antiseptic. Iodine is a frequent cause of poisoning (see iodism). Deficiency of iodine causes goiter. Since iodine salts are opaque to x-rays, they can be combined with other compounds and used as contrast media in diagnostic x-ray examinations of the gallbladder and kidneys.
iodine 123 a radioactive isotope of iodine having a half-life of 13.2 hours and emitting gamma rays and x-rays. It is used in diagnostic imaging and as radiation sources in radiation therapy. Symbol 123I.
iodine 125 a radioisotope of iodine having a half-life of 60.14 days and emitting gamma rays; used as a label in radioimmunoassays and other in vitro tests, and also for thyroid imaging. Symbol 125I.
iodine 131 a radioactive isotope of iodine having a half-life of 8.04 days and emitting beta particles and gamma rays. It is used as a tracer in diagnostic imaging and as a radiation source in radiation therapy. Symbol 131I.
protein-bound iodine a test of thyroid function; see also protein-bound iodine test.
radioactive iodine radioiodine.
iodine solution a transparent, reddish brown liquid, each 100 ml of which contains 1.8 to 2.2 g of iodine and 2.1 to 2.6 g of sodium iodide; a local antiinfective agent.
strong iodine solution Lugol's solution.

pro·tein-bound i·o·dine (PBI),

thyroid hormone in its circulating form, consisting of one or more of the iodothyronines bound to one or more of the serum proteins.

protein-bound iodine

Abbreviation: PBI
Iodine that is attached to serum protein. In the past, thyroid function was tested with a serum measurement of PBI.
See also: iodine
References in periodicals archive ?
The clinical determination of protein-bound iodine. J Clin Invest 1951;30:55-62.
The protein-bound iodine was separated from free iodine by gel filtration on a PD-10 column (Pharmacia) that had been preequilibrated with PBS.
Joe's great interest was thyroid testing, and the Boston Medical Laboratory became the first local commercial laboratory to offer the protein-bound iodine (PBI) test.

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