protein profiling

protein profiling

The detection of the character and quantity of specific sets of proteins in blood or other specimens. Protein profiling has been used as a means of diagnosing specific illnesses, esp. cancers or infectious diseases known to release unique protein patterns into serum. Protein profiling may be used as a means of screening for cancer recurrence in previously treated patients or in patients with multiple risk factors for an illness. It may also aid in the crafting of therapies, e.g., by demonstrating that a particular disease is susceptible to a specific drug therapy. Synonym: protein correlation profiling; serum protein profiling; serum protein-expression profiling
References in periodicals archive ?
Comprehensive Cell Surface Protein Profiling Identifies Specific Markers of Human Naive and Primed Pluripotent States," Cell Stem Cell, 2017; DOI: 10.
The genetic variation of protein profiling is mainly attributed to unique agro-morphological nature of ecotypes as well as their geographical origin.
NMI TT Pharmaservices will be utilising the new and already functional laboratory space to provide life science researchers with its proprietary DigiWest multiplex protein profiling services, to accelerate lead characterisation, disease mechanism and drug mode-of-action analyses and biomarker identification projects for industrial clients and academic partners alike.
sup][15] Here, we enriched low-abundant serum peptides/proteins by WCX magnetic beads and performed serum protein profiling through MALDI-TOF-MS, which offers a wide selection.
The technique, called activity-based protein profiling, has been used in cancer research and allows researchers to track the actual activities of proteins operating within a cell.
12] expressed copper-induced changes in protein profiling of Anabaena doliolum subjected to short- and longterm treatments.
Protein profiling is an emerging independent subspecialty of proteomics that is rapidly expanding and providing unprecedented insight into biological events.
The present study examines the sensitivity of morphological characteristics, photosynthetic capacity and protein profiling of Oryza sativa L.
They also allow reducing of proteome complexity by fractionation, enabling high-throughput quantitative protein profiling.
Among the topics are yeast-based chemical genomic approaches, activity-based protein profiling of cys proteases, using analogue sensitive technologies to target kinases of interest, using split inteins to prepare semi-synthetic proteins and to study the mechanisms of protein trans-splicing, and introducing chemical reporter groups by bio-orthogonal ligation reactions for imaging cell-surface glycans.