protein phosphatases


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pro·tein phos·pha·tas·es

a class of enzymes that catalyze the dephosphorylation of specific phosphorylated proteins.
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Nishimura et al., "Abscisic acid inhibits type 2C protein phosphatases via the PYR/PYL family of START proteins," Science, vol.
Protein phosphatases are associated with many cellular processes including apoptosis, cell cycle progression and so on.
Wip1, a novel human protein phosphatase that is induced in response to ionizing radiation in a p53-dependent manner.
Abbreviations 6-OHDA: 6-Hydroxydopamine AUC: Area under the curve CDK5: Cyclin-dependent protein kinase 5 D1R: Dopamine D1 receptor D2R: Dopamine D2 receptor DA: Dopamine HEK293: Human embryonic kidney 293FT cells MSN: Medium spiny neuron NF-M: Neurofilament medium PD: Parkinson disease PKA: Protein kinase A PKAc: PKA catalytic subunit PP1: Protein phosphatase 1 PSD: Postsynaptic density XIC: Extracted ion chromatogram.
Rubin, "Protein phosphatase 2A positively and negatively regulates Ras1-mediated photoreceptor development in Drosophila," Genes & Development, vol.
Arabidopsis ABA response gene ABI1: features of a calcium-modulated protein phosphatase. Science, 264: 1448-1452
Studies have shown that phytotoxicity of microcystins interferes with metabolism and biomass of aquatic and terrestrial plants, causin reduction of protein phosphatases 1 and 2A, oxidative stress, decrease in photosynthetic activity and even apoptosis.
Gong, "Contributions of protein phosphatases PP1, PP2A, PP2B and PP5 to the regulation of tau phosphorylation," European Journal of Neuroscience, vol.
Casida, "Cantharidin-binding protein: identification as protein phosphatase 2A," Proceedings of the National Academy of Sciences of the United States of America, vol.
Because recombinant HDAC6 binds directly to the protein phosphatase 1 (PP1) catalytic subunit, TSA disrupts endogenous HDAC6-PP1 complexes and activates PP1 (Brush et al., 2004).
Takai, "Inhibitory effect of a marine-sponge toxin, okadaic acid, on protein phosphatases. Specificity and kinetics," Biochemical Journal, vol.

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