Schulman, "Structure-function of the multifunctional Ca2+/calmodulin-dependent protein kinase
II," Biochemical Journal, vol.
Van den Berghe, "Inhibition of fatty acid and cholesterol synthesis by stimulation of AMP-activated protein kinase
," The FASEB Journal, vol.
TC10 has homology sequence with Cdc42 and Rac and binds to effectors having a Cdc42-/Rac-interactive binding domain, such as p21-activated protein kinase
, the neural Wiscott-Aldrich syndrome protein (N-WASP) , and also proteins without these domains, for instance, Exo70 , PIST , and CIP4 .
Moreover, Figure SI also displays the ROC curves of the three most pleiotropic protein kinases
(i.e., PKCA, PKACA, and CK2A1), from which we can get a consistent conclusion.
AMP-activated protein kinase
: new regulation, new roles.
The membranal PIP3, a signaling molecule, recruits and activates proteins that contain the pleckstrin homology (PH) domain such as the phosphoinositide-dependent protein kinase
(PDK) and protein kinase
B (Akt) serine/threonine kinases and the activation of PDK and Akt successively promotes the activation and transcription of their target genes (GSK3, FOXO, BAD, mTOR1, and p53) [89-92].
Cohen, "Phosphorylation of microtubule-associated protein tau by stress-activated protein kinases
," FEBS Letters, vol.
Bax translocates to mitochondria of heart cells during simulated ischaemia: involvement of AMP-activated and p38 mitogen-activated protein kinases
. Biochem J.
Mitogen-activated protein kinase
phosphatases (MKPs) can recognize MAPKs by recognizing the TXY amino acid motif and consequently dephosphorylate and deactivate them.
Muscarinic activation of mitogen-activated protein kinase
in PC12 cells.
PKC and [Ca.sup.2+]/calmodulin-dependent protein kinase
were not activated with glycolipids, indicating that the activation of cAMP-kinase by glycolipids was fairly specific.
The regulation of AMP-activated protein kinase
by upstream kinases.