protein induced by vitamin K absence

pro·tein in·duced by vit·a·min K ab·sence

(PIVKA) (prō'tēn in-dūst' vī'tă-min ab'sĕns)
Nonfunctional protein precursors of the prothrombin group of coagulation factors (e.g., factors II, VII, IX, X). They are synthesized in the liver in the absence of vitamin K and lack the carboxyl (COOH-) group needed to bind the factor to a phospholipid surface.
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