AMBP

(redirected from protein AMBP)

AMBP

A gene on chromosome 9q32-q33 that encodes alpha-1-microglobulin/bikunin precursor protein, which is expressed in liver and secreted in plasma. Alpha-1-microglobulin belongs to the superfamily of lipocalin transport proteins and plays a role in regulating inflammation; bikunin belongs to the superfamily of Kunitz-type protease inhibitors and plays a key role in many physiological and pathological processes, by inhibiting trypsin, plasmin and lysosomal granulocytic elastase, as well as calcium oxalate crystallisation.
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Paragon % Cov Accession score (95) number Entry name Controls 110.11 38.64 P02760 AMBP_HUMAN T1DM 167.84 57.1 P02760 AMBP_HUMAN T2DM 123.92 41.76 P02760 AMBP_HUMAN Peptides Protein name Species (95%) Controls Protein AMBP HUMAN 149 T1DM Protein AMBP HUMAN 337 T2DM Protein AMBP HUMAN 218 Each spot was analysed separately and MS/MS data from the same group were treated as replicates for database analysis.