Huang, "Crystallization of antimicrobial pores in membranes: magainin and protegrin
," Biophysical Journal, vol.
The duo studied the amino acid sequences and three-dimensional structures of over 500 antimicrobial peptides, and found the [gamma]-core structure in molecules as diverse as pea defensins, fruit fly drosomycin, pig protegrin
, and human hepcidin.
This patent addresses the use of antimicrobial peptides, including Protegrin
IB-367, for the treatment of oral mucositis, a severe and painful condition occurring in cancer patients receiving cancer therapies.
has reported in two posters presented at the Interscience Conference on Antimicrobial Agents and Chemotherapy (ICAAC) results of studies on the company's novel antimicrobial peptide compound, Protegrin