Bronchoscopy with bronchoalveolar lavage (BAL) or protected specimen brush (PSB) has shown advantages in the diagnosis of pneumonia in patients on mechanical ventilation .
In conclusion, our findings suggest that the "blind" protected specimen brush has a similar diagnostic yield and specificity to bronchoscopic techniques.
Diagnosis of ventilator-associated pneumonia: Focus on nonbronchoscopic techniques (nonbronchoscopic bronchoalveolar lavage, including mini-BAL, blinded protected specimen brush
, and blinded bronchial sampling) and endotracheal aspirates.
A study of stable and exacerbated outpatients using the protected specimen brush
To rule out infection, bronchoscopy and protected specimen brush
VAP is most accurately diagnosed by quantitative culture and microscopy examination of lower respiratory tract secretions, which are best obtained by bronchoscopically directed techniques such as the protected specimen brush
and bronchoalveolar lavage.