A variety of CTC assays are available and under study, but at present only 1, CellSearch[R] (Veridex/Johnson & Johnson), has undergone full analytical validation for enumeration (6) and been shown in prospective trials
to provide prognostic information at baseline and after treatment in patients with breast, colorectal, or prostate cancer (7-9).
Data Source: A prospective trial
involving 365 patients.
The present investigation examines 2 subgroups of participants from the above-referenced prospective trial
who presented either with or without vulvar erythema at study enrollment prior to being allocated to test and comparison products.
Professor Stephen Duffy, a Cancer Research UK epidemiologist who also worked on the study, said: "The great advantage of CAD is that, if we confirm the very promising results of this study in a prospective trial
, it could help manpower problems in the breast screening service.
This multi-center, prospective trial
will assess the safety and effectiveness of the Genous Bio-engineered R stent in conjunction with optimal statin therapy and will include angiographic follow up at six and 18 months.
To best test the hypothesis that NSAIDs increase the risk for invasive GAS infection, a randomized, prospective trial
should be done.
Randomized prospective trial
of antioxidant supplementation in critically ill surgical patients.
The military commissioner responded with the claim that Congress had authorized McCardle's detention and prospective trial
by military commission.
In contrast to Spark's therapeutic trial, PROSPER should offer the first evidence from a prospective trial
indicating whether statins can prevent mental decline, says Blauw.
A prospective trial
of autologous stem cell transplantation for patients with HIV-associated lymphoma in first complete or partial remission with poor risk features at presentation and for patients who experience disease recurrence after initial treatment is now underway.
Unless you have a randomized prospective trial
, to say that something works based on a few people's experience really isn't fair,'' Gelder said.