prorenin

prorenin

 [pro-ren´in]
the inactive precursor of renin, stored in the juxtaglomerular cells of the kidney and activated by cleavage to renin. Called also big renin.

prorenin

[prōren′in]
the inactive precursor of renin, stored in the juxtaglomerular cells of the kidney and activated by cleavage to renin. Also called big renin.
References in periodicals archive ?
2] Other placental hormones include corticotropin-releasing hormone, endorphins, dynorphins, gonadotropin-releasing hormones, inhibin, leptin, prolactin, and prorenin.
Besides these components, there is prorenin receptor (PRR) which binds renin as well as its precursor, prorenin.
Many studies have reported the presence of members of the Rennin-Angiotensin System (RAS) in the ovary, such as prorenin, angiotensinogen, angiotensin-converting enzyme (ACE), Angiotensin II (Ang II) and Ang II receptors (ATI and AT2), suggesting the involvement of the RAS in ovarian physiology (1).
I am very appreciative to our entire R&D team for developing this unique ELISA kit which for the first time allows for both the rapid and quantitative measurement of human prorenin.
Cross-reactivity of DRC with catalytically active conformations of prorenin is also a concern because the concentration of prorenin, which is normally 10-fold higher than renin, goes up to 100-fold higher in low-renin states such as PA.
3 Prorenin is synthesized and stored in vesicles until cellular signaling results in release of bioactive renin into plasma.
Award for services of Medicinal Chemistry (MC) in a preclinical pharmacological Medikamentenentwicklungzur optimization of antagonists of the renin / prorenin receptor (RER) signaling pathway forthe Charite - UniversitEntsmedizin Berlin.
Laughter increased NK cell activity, lowered prorenin gene expression, and lowered the postprandial glucose level in 34 patients with diabetes, compared with 16 matched controls.
1998) Determinants of interindividual variation of renin and prorenin concentrations: evidence for a sexual dimorphism of (pro) renin levels in humans.
Yuksek duzeylerde prorenin ve angiotensin II, follikul sivi icerisinde saptanmis ve OHSS'lu hastalarin plazma renin seviyeleri yuksek bulunmustur [6].
The real interest in aliskiren will be the insight it provides into "the relationship between prorenin [the biosynthetic precursor of renin] and renin, and its role in modulating the renin angiotensin aldosterone system," said Dr.
Now, a study suggests that a diabetic's prorenin levels may increase significantly 18 months before any vessel damage shows up in the eyes or kidneys.