FFI is a hereditary autosomal dominant prion disease, which is mainly characterized by prominent sleep impairment accompanied by a series of neuropsychiatric disorders, dysautonomia, motor dysfunction, and episodes of peculiar oneiric behaviors (oneiric stupor). Irregular breathing, hypnic jerks, propriospinal
myoclonus at the wake-sleep transition, and quasi-purposeful limb gestures are considered to be core features of FFI.
Plasticity in ascending long propriospinal
and descending supraspinal pathways in chronic cervical spinal cord injured rats.
This effect would be caused by an indirect pathway (i.e., interneuronal systems), including propriospinal
neurons at the C3-C4 level, which mediate corticomotoneuronal inputs to the proximal arm muscles predominantly .
Xiong et al., "Neural stem cell-conditioned medium protects neurons and promotes propriospinal
neurons relay neural circuit reconnection after spinal cord injury," Cell Transplantation, vol.
 a Tet-on system was used to selectively express the synaptotoxin tetanus toxin in propriospinal
(PN) neurons innervated by the motor cortex.
Liu et al., "Autophagy in long propriospinal
neurons is activated after spinal cord injury in adult rats," Neuroscience Letters, vol.
Jessell, "Skilled reaching relies on a V2a propriospinal
internal copy circuit," Nature, vol.
Rabchevsky, "Plasticity of lumbosacral propriospinal
neurons is associated with the development of autonomic dysreflexia after thoracic spinal cord transection," Journal of Comparative Neurology, vol.
Muscle fatigue changes cutaneous suppression of propriospinal
drive to human upper limb muscles.
Buna ilave olarak HBS ve PBH'de retikulospinal eksitator yanitlarda bozulma olmasi spinal jerklere ya da propriospinal
patolojik uyarilara neden oldugu bildirilmistir (9).
It has been proposed that a noxious stimulus can activate various antinociceptive mechanisms, such as diffuse nocicep tive inhibitory control (DNIC) (18), propriospinal
antinociceptive responses (19) and descending modulatory system (20) ; however, the action of calcium channels blockers, [beta]-adrenergic blockers and digoxin on these antinociceptive mechanisms has not been extensively analysed.
(2008): Task Dependent Modulation of Propriospinal
Inputs to Human Shoulder.