propofol


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propofol

 [pro´pah-fol]
a short-acting sedative and hypnotic used as a general anesthetic and adjunct to anesthesia; administered intravenously.

pro·po·fol

(prō'pō-fōl),
An oil-in-water emulsion of 1,6-diisopropylphenol, a hypnotic with rapid onset and short duration of action; used intravenously for induction and maintenance of general anesthesia.
Synonym(s): 2, 6-diisopropyl phenol

propofol

(prō′pō-fôl′, -fōl′)
n.
A rapidly acting sedative and hypnotic drug, C12H18O, administered intravenously to induce and maintain anesthesia or sedation.

propofol

Diprivan® Anesthesiology A versatile nonopioid inhalation sedative-hypnotic with rapid–< 45 secs onset, used to induce and maintain anesthesia, and possibly control refractory status epilepticus; it ↓ intracranial and intraocular pressure, cerebral blood flow, and O2 consumption Pros Ideal for conscious sedation; useful for critically ill Pts; can be combined with other agents–eg, volatile anesthetics, NO2, opiates or benzodiazepines; little post-op N&V Adverse effects Profound respiratory depression ± transient apnea; injection site pain, hypotension Indications Short procedures or outpatient surgery Contraindications Hemodynamically unstable Pts. See Meyer-Overton rule. Cf Inhalation anesthetic, Opioid anesthetic.

pro·po·fol

(prō'pō-fōl)
Hypnotic agent with rapid onset and short duration of action; used intravenously to induce and maintain general anesthesia.

propofol

A general anaesthetic drug given by injection. A brand name is Diprivan.

pro·po·fol

(prō'pō-fōl)
A hypnotic with rapid onset and short duration of action; used intravenously for induction and maintenance of general anesthesia.
Synonym(s): 2,6-diisopropyl phenol, .
References in periodicals archive ?
Painless injection of propofol: pretreatment with ketamine vs thiopental, meperidine, and lidocaine.
To investigate the effect of propofol during sepsis-induced AKI, the mice were randomly divided into 4 groups as follows: i) sham-operated mice (n=12) as control group, ii) CLP group (n=12) injected with normal saline, iii) propofol group (n=12) that received propofol injection (50 mg/kg; twice within 24 h; Sigma-Aldrich, USA) in sham-operated mice, and iv) propofol + CLP group that received propofol injection (50 mg/kg; twice within 24 h) in CLP-operated mice (n=12).
It is well known that there is an inversely proportional relationship between cardiac output and plasma concentrations of propofol. (5,6) This relationship implies that any increase in cardiac output during the maintenance of anesthesia may lower the concentrations of the anesthetic drugs, exposing the patient to a risk of intraoperative awareness.
Seventy-six children agsd 1-6 years who were scheduled to undergo MRI study of the brain for their neurological illnesses over a period of 18 months were recruited After excluding 4 patients, 72children were selects d using centralised computer-generated random numbers to receive either propofol or dexmedetomi dine for sedation.
Propofol (2,6-diisopropylphenol), an intravenously administered anesthetic released for use in 1989, has become popular as an agent for induction and maintenance of anesthesia [7].
Although vegans can ask to be sedated with other drugs that do not contain eggs, anaesthetists say they prefer Propofol because it works very quickly and reliably to put people to sleep and patients wake up faster than with some older drugs.
Moreover, different propofol delivery techniques such as target-controlled infusion (TCI) and syringe pump infusion were used in these studies which may lead to different results.
Officials at Gangnam Police Station in southern Seoul, Thursday, visited the plastic surgery hospital where Lee allegedly received propofol, to check the facts regarding the allegations, together with officials from the regional public health center.
We took this study to know if the haemodynamic changes after laryngoscopy and intubation can be decreased by decreasing the doses of etomidate and propofol together.
Comparing the results of this study, it is concluded that the intravenous therapy of propofol caused a smooth quality of induction and recovery from anesthesia.
(BSE: 500124) (NSE: DRREDDY) (NYSE: RDY) has launched of Propofol Injectable Emulsion, USP, a therapeutic equivalent generic version of Diprivan (propofol) Injectable Emulsion, USP, approved by the US Food and Drug Administration (USFDA), the company said.