pronormoblast


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pronormoblast

 [pro-nor´mo-blast]
a term often considered a synonym of proerythroblast; sometimes limited to one in the course of normal erythrocyte maturation, as opposed to a promegaloblast.

pro·nor·mo·blast

(prō-nōr'mō-blast),
The earliest of four stages in development of the normoblast.
See also: erythroblast.

pronormoblast

/pro·nor·mo·blast/ (-nor´mo-blast) term often considered a synonym of proerythroblast, but sometimes limited to one in a normal course of erythrocyte maturation, as opposed to a promegaloblast.

pro·nor·mo·blast

(prō-nōr'mō-blast)
The earliest of four stages in development of the normoblast.
See also: erythroblast
Synonym(s): proerythroblast, rubriblast.

pronormoblast

the earliest erythrocyte precursor, having a relatively large nucleus containing several nucleoli, surrounded by a small amount of cytoplasm (see also normoblast). Called also proerythroblast and rubriblast.
References in periodicals archive ?
On investigation, neutropenia was detected and bone marrow stained smear had giant pronormoblasts (lantern cell) (Fig.
The same patient also had giant pronormoblasts or "Lantern cell" in bone marrow aspirate and which is suggestive of B19 infection (25).
Bone marrow examination shows normocellularity with findings of profound depletion of erythroid cells, abnormal very large pronormoblasts and normoblasts exhibiting intranuclear eosinophilic inclusion bodies (Lampion or Lantern cells).
In M6b, 30% or more pronormoblasts were present, with an insignificant myeloblastic component.
In the process of erythropoiesis, erythroid cells matures from pronormoblasts, characterised by the loss of nucleus, condensation of chromatin to form coalescent clumps, formation of siderotic clusters, and the cessation of DNA and RNA synthesis, and optimized haemoglobin production.