prolactinoma


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prolactinoma

 [pro-lak″tĭ-no´mah]
a pituitary adenoma made up of lactotrophs that secretes excessive amounts of prolactin; this may delay puberty in either sex, cause galactorrhea-amenorrhea syndrome in women, or decrease libido and fertility in men. Called also prolactin cell or prolactin-secreting adenoma and lactotrope or lactotroph adenoma.

pro·lac·tin-·pro·duc·ing ad·e·no·ma

a pituitary adenoma composed of prolactin-producing cells; it gives rise to symptoms of nonpuerperal amenorrhea and galactorrhea (Forbes-Albright syndrome) in women and to impotence in men.
Synonym(s): prolactinoma

prolactinoma

/pro·lac·ti·no·ma/ (-lak″tĭ-no´mah) a pituitary adenoma that secretes prolactin.

prolactinoma

Endocrinology A pituitary tumor more common in Pts < age 40 characterized by an excess secretion of prolactin–tumor size correlates with the prolactin level; smaller tumors, microprolactinomas, are more common in ♀; macroprolactinomas are more common in ♂ and associated with sexual dysfunction; women may become symptomatic while on OCs; menses may stop when OCs are discontinued; prolactinomas may grow during pregnancy and be diagnosed postdelivery. See Prolactin.

pro·lac·tin-pro·duc·ing ad·e·no·ma

(prō-lak'tin-prŏ-dūs'ing ad'ĕ-nō'mă)
A pituitary adenoma composed of prolactin-producing cells; it gives rise to symptoms of nonpuerperal amenorrhea and galactorrhea (Forbes-Albright syndrome) in women and to impotence in men.
Synonym(s): prolactinoma.

prolactinoma

A benign tumour of the PITUITARY GLAND that secretes large quantities of the hormone PROLACTIN. The tumour can cause blindness by pressing on the OPTIC CHIASMA and may be suspected because of unexpected milk production (lactation). Treatment is by surgery or by drugs.

prolactinoma (prōˈ·lak·t·nōˑ·m),

n a noncancerous tumor of the pituitary gland, most often in women, that leads to excess production of prolactin, the hormone responsible for modulating lactation. Also called
secreting adenoma.
References in periodicals archive ?
The patient was subsequently taken to the operating room for a second transsphenoidal excision of the presumed recurrence of pituitary prolactinoma.
Menstrual disorders and infertility in women with prolactinoma are often diagnosed earlier (Di Luigi, 2003).
Exogenous steroid administration remains the main etiology while endogenous steroid production, obesity, hypothyroidism, pituitary prolactinoma and idiopathic causes may also occur.
Surgery is also recommended when the incidentaloma is abutting or compressing the optic nerves or chiasm on magnetic resonance imaging, when a patient is experiencing pituitary apoplexy with visual disturbance, or if a patient has a hypersecreting tumor other than a prolactinoma, according to the guidelines, which appear in the Endocrine Society's journal (J.
Some forms of big big prolactin behave as a complex of monomeric prolactin with an immunoglobulin G in patients with macroprolactinemia or prolactinoma.
The possibility of a prolactinoma undergoing apoplexy, as has been reported previously (15), also seems less likely, because the patient did not have any menstrual disturbances, galactorrhea or infertility prior to conception.
Pituitary prolactinoma with T cell rich inflammatory infiltrate: a possible example of antitumoral immune response to be differentiated from lymphocytic hypophysitis.
SAN FRANCISCO -- Complications from a prolactinoma during pregnancy are best avoided by treating the adenoma before conception.
2) Spinal epidural lipomatosis has been associated with Cushing's disease, Cushing's syndrome, hypothyroidism, pituitary prolactinoma, radiotherapy, obesity, and idiopathic causes.
This is especially true of the diagnosis of prolactinoma because confirmatory imaging techniques are insensitive and nonspecific.
In this case, without a tissue diagnosis and with serum prolactin levels of 3-5,000 mU/l, the tumour was most likely to have been a non-functional prolactinoma (8).