The herbal formula performed as well as the prokinetic drug
for functional dyspepsia and was superior to metoclopramide in a retrospective cohort study of 961 patients.
Metoclopramide, a prokinetic drug
used for more than 40 years to treat nausea and vomiting due to various causes, is one alternative to the doxylamine-pyridoxine combination.
A randomised clinical trial comparing the efficacy of a herbal preparation STW5 with the prokinetic drug
cisaprid in patients with dysmo-tility type of functional dyspepsia.
Metoclopramide is another popular prokinetic drug
that hastens stomach emptying of solid and liquid meals into the small intestines.
Peter Stein, Chairman and CEO of Norgine said, "There is a critical need for a new, safe and effective prokinetic drug
for use in acute care settings, as there are no satisfactory treatments on the market.
each year, as well as for other indications in acute settings where an intravenous prokinetic drug
Should Axcan achieve sales corresponding to only 25% of 1999 sales of Cisapride, a prokinetic drug
marketed by a leading pharmaceutical company for patients with heartburn and esophagitis due to GERD, ITAX(TM) would become by far Axcan's largest product," he concluded.
DDP733 is an oral prokinetic drug
which Dynogen is developing as a treatment for both IBS-c and nocturnal gastroesophageal reflux disease (NGERD).
TZP-102 is a second generation prokinetic drug
that Tranzyme intends to develop for the treatment of mild-to-moderate gastroparesis and other chronic GI motility disorders.
In small mammals, intussusception may be caused by enteritis, prokinetic drugs
, or exercise, or it may be an agonal event.
There is a compelling need for new treatments for lower GI functional disorders, but there are no safe and effective prokinetic drugs
currently approved for these conditions in the U.
Treatment is aimed at reducing GER through dietary modification, proton-pump inhibitors, and prokinetic drugs