progressive multifocal leucoencephalopathy

progressive multifocal leucoencephalopathy

A rare brain disorder featuring widespread patches of DEMYELINATION and changes in the supportive (glial) cells suggestive of a papova virus infection. There is severe brain damage and the condition usually progresses to death within a few weeks.
References in periodicals archive ?
Shah, "Progressive multifocal leucoencephalopathy isolated to the posterior fossa," BMJ Case Reports, vol.
This includes Cryptococcal meningitis, Toxoplasmosis, Guillain-Barre syndrome, Pyogenic meningitis, Cytomegalovirus encephalitis, Progressive multifocal leucoencephalopathy, Hypertensive stroke (Ischaemic/haemorrhagic) and Communicating hydrocephalus; however, we had excluded Tubercular meningitis to group into extrapulmonary tuberculosis.
The significant risk in the second-line drugs that Modi refers to is a condition known as progressive multifocal leucoencephalopathy (PML), caused by activation of what's called the JC virus in the brain--which can be fatal.
Dessel, "Cultivation of papova-like virus from human brain with progressive multifocal leucoencephalopathy," The Lancet, vol.
Progressive multifocal leucoencephalopathy. N Eng J Med 1961;265;815-823.
HIV-associated neuro-cognitive disorder EBV: primary CNS lym-phoma JC virus: PML [not equal to] Prions: spongiform ence- phalopathy Spinal Acute viral HIV-1 vacuolar cord myelitis myelopathy ADEM * HTLV-1 myelopathy * Acute disseminated encephalomyelitis [dagger] Subacute sclerosing panencephalitis [not equal to] Progressive multifocal leucoencephalopathy.
There were no cases of progressive multifocal leucoencephalopathy, cytomegalovirus or pneumocystis pneumonia.
Spinal demyelination in progressive multifocal leucoencephalopathy. Neurology, 1969, 19, 287-288.
Major et al., "Monoclonal antibody-associated progressive multifocal leucoencephalopathy in patients treated with rituximab, natalizumab, and efalizumab: a review from the Research on Adverse Drug Events and Reports (RADAR) Project," The Lancet Oncology, vol.
Several reports confirmed its substantial effectiveness in relapsing-remitting MS and, over a year after its reintroduction to the market, no further cases of progressive multifocal leucoencephalopathy have occurred although long- term follow up will be necessary.
Progressive multifocal leucoencephalopathy (PML) is a demyelinating disease caused by the human neurotropic JC (John Cunningham) virus, a polyomavirus.
Janota, "Progressive multifocal leucoencephalopathy: remission with cytarabine," Journal of Neurology Neurosurgery and Psychiatry, vol.
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