progressive disease


Also found in: Acronyms.

progressive disease

Medspeak
Any chronic or dread disease (e.g., cancer), which progresses with time in scope and/or severity.

Oncology
A term defined in the context of clinical trials as tumour growth of ≥ 20% since treatment began, including local or metastatic tumour mass.

progressive disease

Medtalk A chronic or dread disease–eg, CA, which ↑ with time in scope or severity. See Dread disease.
References in periodicals archive ?
If the nephrology community would cease to use the word "stable" to describe a progressive disease state, patients would almost certainly have improved outcomes.
The fourth-leading cause of death in the United States, COPD is a slowly progressive disease characterized by the obstruction of airflow to the lungs.
All the mice fed an inert substance showed progressive disease.
It is a slowly progressive disease of the nervous system resulting from a specific impairment or imbalance in the nervous system (Page 33, December 17).
The first connection was made in the early 1980s, when young people illegally taking an impure form of Demerol (MPTP) exhibited symptoms of an advanced form of this progressive disease.
Parkinson disease is a progressive disease of the nervous system that can cause trembling or shakiness, rigid muscles, slowed movement, and impaired balance.
Because Alzheimer's is a progressive disease, some facilities subdivide their Alzhemer's population.
In this form of MS, relapsing-remitting MS converts into progressive disease and people experience steady loss of functions, sometimes accompanied by relapses and partial recoveries.
An anguished and skeptical man facing an uncertain prognosis of a progressive disease, and disillusioned in love, he drowned himself in the Dvina River.
In the trial, CB7630 was administered once daily to chemotherapy-naove patients with castration refractory prostate cancer (CRPC), who had progressive disease despite treatment with LHRH analogues and multiple other hormonal therapies including antiandrogens, diethylstilboestrol and dexamethasone.
Biopharmaceutical company Bristol-Myers Squibb Company (NYSE:BMY) disclosed on Tuesday the receipt of approval from the European Commission for ORENCIA intravenous (IV) infusion and subcutaneous (SC) injection, in combination with methotrexate (MTX), for the treatment of highly active and progressive disease in adult patients with rheumatoid arthritis (RA) not previously treated with MTX.

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