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A small protein that binds to monomeric actin (thus becoming profilactin), preventing premature polymerization of actin. It also participates in the inhibition of one isoform of phospholipase C.
References in periodicals archive ?
Our previous studies showed that immunization of broilers at day 18 of embryogenesis with the Eimeria recombinant profilin protein induced protection against post-hatch challenge infection with live parasites [19,20].
Overexpression of a Profilin (GhPFN2) promotes the progression of developmental phases in cotton fibers.
A new mouse model of ALS because of profilin mutation indicates the disease can develop when a cell transport protein called actin cannot form long chains.
Actin-binding proteins such as profilin [101] and cofilin [102] are also subject to S-nitrosylation and may contribute through the latter modifications to modulate the remodelling of the actin network.
She says she tried not to take sides when the company split into proFilin and pro-Dmitrichenko camps.
For example, in eluates we found proteins involved in the regulation of cell adhesion and cytoskeleton organization: the actin cytoskeletal (gi/10939908) and profilin (gi/89440162).
These proteins include (i) calcium-binding protein MRP14 implicated in several types of cancer; (ii) CD59 overexpressed on tumour cells that enables them to escape from complement-dependent and antibody-mediated immune responses; (iii) Profilin 1, a protein involved in several signaling pathways with cytoplasmic and nuclear ligands, generally secreted into tumour microenvironments during the early progressive stage of tumorigenesis; and (iv) catalase, a member of the enzymatic antioxidative system, whose level is elevated in many human tumours and involved in carcinogenesis and tumour progression (109).
Kognitif ya da davranissal profilin belirlenmesi sadece tani icin degil ayni zamanda hasta ve ailesine bozuklugun dogasini aciklamakve cozume yonelik girisimler uretmek icin de gereklidir.
The role of profilin complexes in cell motility and other cellular processes.
Parietaria profilin shows only limited cross-reactivity with birch and grass profilins.
Research and review articles describe molecular pathways for renal tubular epithelial call apoptosis, actions of complex element-binding proteins, the molecular pathogenesis of influenza virus infection (including apoptosis induction and macrophage activation), signaling cascades in cell death and survival, profilin as an allergen and tumor suppression device, sophisticated yeast therapy, nuclear calcium signals, and the signaling network of Ras family and Rho family binding proteins in mammalian cells.