proerythroblast


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proerythroblast

 [pro″ĕ-rith´ro-blast]
the earliest erythrocyte precursor in the erythrocytic series, preceding the basophilic erythroblast and having a large nucleus containing several nucleoli, surrounded by a small amount of cytoplasm. The term may encompass both normal and abnormal red cell precursors, in which case the two types may be called pronormoblast and promegaloblast, or it may be used to mean a normal precursor only, as synonymous with pronormblast. Called also rubriblast.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

pro·nor·mo·blast

(prō-nōr'mō-blast),
The earliest of four stages in development of the normoblast.
See also: erythroblast.
Farlex Partner Medical Dictionary © Farlex 2012

pro·nor·mo·blast

(prō-nōr'mō-blast)
The earliest of four stages in development of the normoblast.
See also: erythroblast
Synonym(s): proerythroblast, rubriblast.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
The presence of polymorphic granules in organic proerythroblasts indicates the activity of acid phosphatase and a low degree of cell proliferation.
As the erythrocyte progenitors develop into the first recognizable erythrocyte precursors, or proerythroblasts, EPO receptors are lost, and the cells begin to express a tremendous number of transferrin receptors (300,000 to 400,000/cell) (Fauci et al., 2008).
Maturation of erythroid cells started with the expression of CD71 ([CD71.sup.+]/[Ter119.sup.-] cells) in the proerythroblasts. CD71high/Ter119- cells: late erythroblasts; [CD71.sup.+]/[Ter119.sup.+] cells: reticulocytes; [CD71.sup.-]/[Ter119.sup.+]: mature red blood cells.
It is possible that because of postoperative erythrocyte loss, bone marrow proerythroblasts proliferate and differentiate into mature erythrocytes, which take approximately 5 days to occur.
Novel cytomorphology of the giant proerythroblasts of parvovirus B19 infection.
Diagnosis and characterization of acute erythroleukemia subsets by determining the percentages of myeloblasts and proerythroblasts in 69 cases.