product ion scan

product ion scan

In a multistage mass spectrometry (MS/MS) experiment, mass-selected precursor ions are induced to dissociate into product ions, which are then mass analysed by a second analyser.

The product ion scan is one of three common scans in the single-step MS/MS experiment, in which the first mass analyser is set at the mass of the selected precursor ion; the second mass analyser is then scanned from that mass downwards, resulting in a mass spectrum that contains signals for all the product ions formed from the selected precursor ion.
References in periodicals archive ?
Sensitive and qualitative analysis of isomeric and isobaric plant metabolites was achieved by developing a MRM and MRM-dependent product ion scan (PIS) method.
Each fragment, isolated from the product ion scan, was fragmented again in the LIT to look for secondary ion candidates.
For pseudo-[MS.sup.3], an initial MS2 scan followed by a product ion scan of each compound was performed to distinguish the parent ion peaks as well as the fragment ions of compounds 4a-j.
An initial MS/MS scan followed by a product ion scan of each compound was performed to distinguish the parent ion peaks and the fragment ions of compounds 3a-h.
For example, the definition of "product ion scan' is repeated twice, whereas the term "product ion' is not actually defined.
They include product ion scans to detect expected metabolites, as well as precursor ion scans and neutral loss scans to detect both expected and unexpected metabolite ions.
A maximum of 4 candidate ions were selected for subsequent product ion scans based on signal intensity.
Product ion scans of VMA and [d.sub.3]-VMA calibrators were collected in continuous flow mode as described previously (4,5).
MS/MS product ion scans of MMA and succinate standards were collected in continuous flow mode by connecting an infusion pump directly to the TurboIonSpray probe.

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