proconvertin


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Related to proconvertin: Christmas factor, antihemophilic factor

proconvertin

 [pro″kon-ver´tin]

fac·tor VII

in the clotting of blood, also known as: proconvertin (Owren), convertin, serum prothrombin conversion accelerator (de Vries, Alexander), stable factor (Stefanini), cofactor V (Owren), prothrombinogen (Quick), cothromboplastin (Mann and Hurn), serum accelerator (Jacox). Factor VII forms a complex with tissue thromboplastin and calcium to activate factor X. Factor VII is known to be involved in: the congenital deficiency of factor VII, with purpura and bleeding from mucous membranes, autosomal recessive inheritance; the acquired deficiency of factor VII in association with a deficiency of vitamin K, neonatal patients, and the administration of prothrombinopenic drugs; the acquired excess of factor VII in some patients with thromboembolism. It accelerates the conversion of prothrombin to thrombin, in the presence of tissue thromboplastin, calcium, and factor V.

factor VII

A coagulation factor that forms a complex with thromboplastin and calcium to activate factor X.

fac·tor VII

(fak'tŏr)
A plasma factor in blood coagulation, forms a complex with tissue thromboplastin and calcium to activate factor X; accelerates the conversion of prothrombin to thrombin, in the presence of tissue thromboplastin, calcium, and factor V.
Synonym(s): cothromboplastin, proconvertin, serum accelerator, serum prothrombin conversion accelerator.

fac·tor VII

(fak'tŏr)
In blood clotting, forms a complex with tissue thromboplastin and calcium to activate factor X.
Synonym(s): prothrombinogen.