procarcinogen

procarcinogen

 [pro″kahr-sin´o-jen]
a chemical substance that becomes a carcinogen only after it is altered by metabolic processes.

procarcinogen

/pro·car·cin·o·gen/ (-kahr-sin″ah-jen) a chemical substance that becomes carcinogenic only after it is altered by metabolic processes.

procarcinogen

(prō″kar-sin′ŏ-jĕn) [ pro- + carcinogen]
An agent that may cause cancer only after it is metabolized within an organism.

procarcinogen

a chemical substance that becomes carcinogenic only after it is altered by metabolic processes.
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References in periodicals archive ?
There are some metabolic pathways which lead to inactivation of procarcinogen or its derivatives.
Researchers from the University of California, San Diego School of Medicine, say the chemical disrupted liver integrity and compromised liver function in mice models that were given a procarcinogen to promote liver cancer.
It may also play an indirect role in the conversion of procarcinogen to the ultimate carcinogens (9, 10, 11).
It also causes recurrent kidney stones; is a probable procarcinogen for gastric cancer; and has a pathophysiologic basis for causing osteoporosis, obesity, cardiovascular disease independent of blood pressure, and increased severity and frequency of asthma attacks (1).
That's right, and (very unfortunately for the men involved) my observation has been that many men who take finasteride to suppress procarcinogenic DHT end up suppressing their own anticarcinogenic 3 [beta] -Adiol even more, thus shifting the procarcinogen (DHT) to anticarcinogen (3 [beta] -Adiol) ratio toward a greater risk of cancer.
The studies clearly indicated that the administration of zinc in the presence of procarcinogen 1, 2 dimehtylhydrazine (DMH) brings about decrease in tumour incidence and tumour burden as well as profound alterations in the antioxidant status with restoration of normal colonic histoarchitecture.
However, the interactions between ethanol metabolism and procarcinogen metabolism are complex and may depend, among other factors, on the degree of CYP2E1 induction, the chemical structure of the procarcinogen, and the presence or absence of ethanol in the body during procarcinogen metabolism.
People with low CYP2A6 activity also seem to have a reduced risk for lung, gastric, oral, and colorectal cancers, because CYP2A6 is known to activate procarcinogen nitrosamines and other compounds in cigarette smoke into carcinogens.
Individuals with low CYP2A6 activity also appear to have a reduced risk for lung, gastric, oral, and colorectal cancers, because CYP2A6 is known to activate procarcinogen nitrosamines and other compounds in cigarette smoke into carcinogens.
However, a high fat diet and dysbiosis (alterations in gut ecology) may allow the accumulation of lithocholic acid, which acts as an oxidant, irritant, mutagen, and procarcinogen.
2000), is a procarcinogen formed in the process of incomplete combustion of organic materials (Gelboin 1980).