Compounds or agents capable of generating toxic oxygen species. Compare: antioxidant.
Farlex Partner Medical Dictionary © Farlex 2012
References in periodicals archive ?
There is a nutritional analogy to this line of thinking: antioxidants are good for your health but in excess they flip and turn into pro-oxidants. They end up doing exactly the opposite and cause irrevocable damage to the very mechanisms and organs they were meant to protect in the first instance".
Macrophage foam cell formation during early atherogenesis is determined by the balance between pro-oxidants and anti-oxidants in arterial cells and blood lipoproteins.
Sodium nitroprusside or iron as pro-oxidants stimulate the production of TBARS in mice liver and cause lipid peroxidation.
These antioxidants theoretically protect us from damage by pro-oxidants.
These antioxidants theoretically protect us from damage by pro-oxidants. But that explanation may be incorrect.
However, in certain situations, antioxidants can become pro-oxidants and will elicit the opposite effect to what is desired.
Few publications have discussed about the photo-oxidation of PP in the presence of pro-oxidants [11].
Again, we emphasize that these results are only suggestive that medication use (corticosteroids) may reduce the FeNO response induced by the pro-oxidants of PM.
(1) as a disturbance between the pro-oxidant and antioxidant balance in favor of the pro-oxidants.
While the study's results have not yet been tested in people, they raise the possibility that cancer should be treated with pro-oxidants and that cancer patients should not supplement their diet with large doses of antioxidants.
Intrinsically, cancer cells have higher basal levels of ROS which if supplemented by additional oxidative insult by pro-oxidants can be cytotoxic, an example being Malabaricone-A (MAL-A).