primordial germ cell


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pri·mor·di·al germ cell

the earliest undifferentiated sex cell, found initially outside the gonad.
Synonym(s): gonocyte

primordial germ cell

A germ cell before it begins its maturation into a haploid gamete.
Synonym: primordial cell
See also: cell
References in periodicals archive ?
Since primordial germ cells undergo erasure of imprinting during germline development, this difference further suggests that Type I GCTs may arise from an earlier stage of development compared to Type II GCTs [14].
Primordial germ cells (PGCs) are the precursors of adult germ cells and have remarkable potential in developmental biology-, disease modelling-, and drug development-related research applications [4].
The fine morphology of mouse primordial germ cells in extragonadal locations.
Autocrine and paracrine mechanisms regulating primordial germ cell proliferation.
Hogan, "Derivation of pluripotential embryonic stem cells from murine primordial germ cells in culture," Cell, vol.
Although the exact causative factor of germ cell tumors is not known, the hypothesis is that the disease process starts in fetal life and consists of abnormal proliferation of primordial germ cells. [4,5]
Germ cell neoplasms arise from primordial germ cells of the gonad that differentiate to embryonic and extraembryonic tissues.
Moreover, left testis was seen non-significantly heavier than the right testis in 80% of the birds The basis for testicular asymmetry remains unknown but may be due to an unequal number of primordial germ cells incorporated into the embryonic gonads (Tyler and Gous, 2008).
Stem cells gathered from mouse embryos and plunged into a bath of chemicals turn into sperm mother cells known as a primordial germ cells.
Germ cell tumors are derived from the primordial germ cells of the ovary.
A vasa ortholog has been isolated and used as a molecular marker to detect primordial germ cells (PGC) and other germ line cells from many animals, e.g., in Caenorhabditis elegans (Roussel & Bennett 1993), Xenopus laevis (Komiya et al.