Since primordial germ cells
undergo erasure of imprinting during germline development, this difference further suggests that Type I GCTs may arise from an earlier stage of development compared to Type II GCTs .
Primordial germ cells
(PGCs) are the precursors of adult germ cells and have remarkable potential in developmental biology-, disease modelling-, and drug development-related research applications .
(2002) Epigenetic reprogramming in mouse primordial germ cells
The fine morphology of mouse primordial germ cells
in extragonadal locations.
Autocrine and paracrine mechanisms regulating primordial germ cell
Hogan, "Derivation of pluripotential embryonic stem cells from murine primordial germ cells
in culture," Cell, vol.
Although the exact causative factor of germ cell tumors is not known, the hypothesis is that the disease process starts in fetal life and consists of abnormal proliferation of primordial germ cells
Germ cell neoplasms arise from primordial germ cells
of the gonad that differentiate to embryonic and extraembryonic tissues.
Moreover, left testis was seen non-significantly heavier than the right testis in 80% of the birds The basis for testicular asymmetry remains unknown but may be due to an unequal number of primordial germ cells
incorporated into the embryonic gonads (Tyler and Gous, 2008).
Stem cells gathered from mouse embryos and plunged into a bath of chemicals turn into sperm mother cells known as a primordial germ cells
Germ cell tumors are derived from the primordial germ cells
of the ovary.
A vasa ortholog has been isolated and used as a molecular marker to detect primordial germ cells
(PGC) and other germ line cells from many animals, e.g., in Caenorhabditis elegans (Roussel & Bennett 1993), Xenopus laevis (Komiya et al.