primase


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pri·mase

(prī'māz),
A polymerase that acts on a template DNA strand to produce RNA, resulting in the formation of an RNA primer needed in RNA replication.
Synonym(s): dnaG
[primer + -ase]
Farlex Partner Medical Dictionary © Farlex 2012

primase

an ENZYME that synthesizes RNA PRIMERS during DNA replication in bacteria and certain single-stranded DNA phages. The RNA primers can then be extended by DNA POLYMERASE (see DNA (b) REPLICATION).
Collins Dictionary of Biology, 3rd ed. © W. G. Hale, V. A. Saunders, J. P. Margham 2005
References in periodicals archive ?
Although archea primase is similar to the eukaryotic primase, it is a heterodimer which lacks the two subunits of DNA polymerase (Rowen & Kornberg, 1978).
Active site mapping of the catalytic mouse primase subunit by alanine scanning mutagenesis.
Ello, ademas de incidir en el tema de la fortaleza de las comunidades pese a las diferentes reformas agrarias y a las narrativas de degradacion de lo indio, tambien explica en parte que en las disputas interetnicas primase la negociacion frente a la imposicion (Mendez, (coord.), 2006, 13-95; Brienen, 2011).
SAN DIEGO - Helicase primase inhibitors, such as the investigational drug ASP2151, could offer an alternative therapeutic approach in the treatment genital herpes.
Several of the other most conserved proteins encoded are enzymes, including helicase A859L (>95% identity), RNA helicase B962L (>95% identity), prenyltransferase B318L (>95% identity), RNA polymerase 6 C147L (>96% identity), and DNA primase C962R (>97% identity).
The enzyme primase constructs primers by complimentary base-pairing with the single-stranded DNA.
Asegurar la equidad intergeneracional en materia de acceso a los derechos basicos deberia ser una de las prioridades politicas y sociales del siglo XXI si no primase una concepcion utilitarista de la racionalidad economica.
So the cell has another enzyme called a primase that actually makes the first few nucleotides of the copy.
There is a wide list of phytochemicals which act as inhibitors and a few of them are glycosylated flavones suppressing topoisomerase IV activity (Bernard et al., 1997), myricetin inhibiting DnaB helicase (Griep et al., 2007), allicin inhibiting RNA synthesis (Feldberg et al., 1988) and compounds from the plant Polygonum cuspidatum inhibiting bacterial DNA primase (Hegde et al., 2004).