primary reninism


a condition marked by overproduction of renin.
primary reninism a syndrome of hypertension, hypokalemia, hyperaldosteronism, and elevated plasma renin activity, due to proliferation of juxtaglomerular cells.

pri·mar·y re·nin·ism

(prī'mār-ē re'nin-izm),
Overproduction of renin by juxtaglomerular cells in the absence of a stimulus (for example, decreased renal perfusion); leads to hyperaldosteronism, hypertension, hypokalemia, and edema.
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