primary irritant

pri·mar·y ir·ri·tant

a substance that causes inflammation and other evidence of irritation, particularly of the skin, on first contact or exposure, or as a reaction to cumulative contacts, not dependent on a mechanism of sensitization.
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Such groups continue to act as the primary irritant in Afghan-Pakistan bilateral relations.
In most cases, these signs, which are essentially those of a primary irritant dermatitis, are accompanied by symptoms that, in the mildest cases, may only be slight soreness and/or irritation but may progress to quite unpleasant burning discomfort.
In staffing firm Randstad USA's survey of employee pet peeves, office gossip was the top vote-getter, with 60 percent of respondents citing it their primary irritant.
Survey Says: Since poor service is surveyors' number one complaint nationally, it comes as no surprise that 72% singled out shoddy service as their primary irritant.
Ozone, formed by the interaction of hydrocarbons and nitrogen oxides, is the primary irritant in urban smog.
They reported that a primary irritant is being asked by the operator to repeat call details after they have given this information one or more times to the operator or an automated system.
And this year, the National Weather Services's latest forecast envisions above-normal temperatures -- the type that can cook up high levels of ozone, the primary irritant in smog--from July to October for one-third of the nation.
Ozone, the primary irritant is smog, forms in the lower atmosphere when sunlight reacts with hydrocarbons and nitrogen oxides.
Tha latter could have serious implications for human exposure to ozone -- the primary irritant in smog.
The federal air-quality standard for ozone--the primary irritant in smog-- was developed primarily from human health-effects data showing that the chemical might aggravate existing respiratory problems.
Ozone is not the only photochemically produced oxidant, but EPA has decided to focus on it as the primary irritant in smog -- the assumption being that reducing ozone production will simultaneously reduce the production of related photochemical oxidants.
Probably the best-known primary irritants in personal care and cosmetics are detergents with sodium lauryl sulfate (SLS) being the utmost recognized.

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